经皮微创气管切开术对喉癌患者应激指标的影响  

Effects of minimally invasive percutaneous tracheotomy on stress indicators in patients with laryngeal cancer

作　　者：李琴 LI Qin(Sichuan Provincial General Hospital of Judicial Police Officers,Chengdu,Sichuan 610000,China)

机构地区：[1]四川省司法警官总医院,四川成都610000

出　　处：《中国国境卫生检疫杂志》2021年第S01期39-40,共2页Chinese Journal of Frontier Health and Quarantine

摘　　要：目的探讨经皮微创气管切开术应用于喉癌患者中的效果。方法选取2019—2021年间我院收治的62例喉癌手术患者,以随机数字表法均分为参照组和研究组。参照组行传统气管切开术,研究组行经皮微创气管切开术,比较两组应激指标及不良反应差异。结果两组气管切开置入导管后即刻(T2)、术毕(T3)及拔管后30min(T4)白细胞介素-6、血糖水平、皮质醇以及C反应蛋白明显高于麻醉前(T1)(P<0.05)。较参照组,研究组T2、T3、T4的各项应激指标水平明显更低(P<0.05),皮下气肿、切口渗血、气道梗阻等不良反应发生率更低(P<0.05)。结论经皮微创气管切开术应用于喉癌患者中对应激反应指标影响更小,不易产生不良反应,建议优先使用。Objective To investigate the effect of minimally invasive percutaneous tracheotomy in patients with laryngeal cancer.Methods A total of 62 patients undergoing laryngeal cancer surgery in our hospital from 2019 to 2021 were selected and divided into reference group and study group by random number table method.The control group received traditional tracheotomy,and the study group received percutaneous minimally invasive tracheotomy.The stress indexes and adverse reactions of the two groups were compared.Results The levels of interleukin-6,blood glucose,cortisol and C-reactive protein in both groups were significantly higher than those before anesthesia(T1)immediately after tracheotomy(T2),after surgery(T3)and 30 min after extubation(T4)(P<0.05).Compared with the control group,the levels of various stress indicators of T2,T3 and T4 in the study group were significantly lower(P<0.05),and the incidence of subcutaneous emphysema,incision bleeding,airway obstruction and other adverse reactions was lower(P<0.05).Conclusion The application of percutaneous microinvasive tracheotomy in patients with laryngeal cancer has less impact on stress response indicators and is less likely to produce adverse reactions.Therefore,it is recommended to use it first.

关 键 词：经皮微创气管切开术 喉癌 应激指标 不良反应 

分 类 号：R183[医药卫生—流行病学]