富血小板血浆疗法治疗孤立性腰椎小关节综合征的临床疗效分析  

Clinicaleffect of platelet rich plasma therapy in the treatment of isolated lumbar facet joint syndrome

作　　者：赵付显 廖文胜 钱重阳[1] ZHAO Fu-xian;LIAO Wen-sheng;QIAN Chong-yang(Department of Orthopedics,General Hospital of Zhengzhou Coal Industry(Group)Co.,Ltd,Zhengzhou,Henan 452371,China)

机构地区：[1]郑州煤炭工业(集团)有限责任公司总医院骨科,河南郑州452371

出　　处：《颈腰痛杂志》2022年第2期201-203,207,共4页The Journal of Cervicodynia and Lumbodynia

摘　　要：目的探讨富血小板血浆(platelet rich plasma,PRP)疗法治疗孤立性腰椎小关节综合征(lumbar facet joints syndrome,LFJS)的临床疗效。方法选择2017年9月~2019年5月在本院就诊的88例LFJS患者,采用随机数字表法分为对照组和观察组各44例。对照组给予超声引导下关节腔注射类固醇联合局麻药物,观察组给予超声引导下关节腔注射PRP治疗,观察两组治疗成功率、治疗时间、并发症发生情况,比较两组治疗前和治疗后1、3、6个月时的疼痛VAS评分,采用Oswestry功能障碍指数(Oswestry disability index,ODI)评估两组患者治疗前、治疗后3个月、6个月时的腰部功能。结果治疗后1、3、6个月时,两组患者VAS评分均显著低于治疗前(P<0.05);治疗后1个月时,观察组VAS评分显著高于对照组,治疗后3、6个月时观察组VAS评分显著低于对照组,差异均有统计学意义(P<0.05)。治疗后3、6个月时,观察组患者ODI指数均显著降低(P<0.05),且显著低于对照组,差异有统计学意义(P<0.05)。两组均未见严重并发症发生。结论PRP治疗单纯LFJS的早期疗效逊于类固醇和局麻药,但随着时间延长,其疗效逐渐优于类固醇和局麻药,值得临床推广应用。Objective To investigate the clinical efficacy of platelet rich plasma(PRP)in the treatment of simple lumbar facet joint syndrome(LFJS).Methods From September 2017 to May 2019,88 patients with LFJS in our hospital were selected and randomly divided into the control group and the observation group,with 44 cases in each group.The control group was given ultrasound-guided intra-articular steroid injection combined with local anesthetic drugs,and the observation group was given ultrasound-guided intra-articular PRP injection.The success rate,treatment time and complications of the two groups were observed,and the VAS scale before treatment,1 month,3 months and 6 months after treatment were compared.Oswestry disability index(ODI)was used to evaluate the lumbar function of the two groups before treatment,3 months and 6 months after treatment.Results After 1 month,3 months and 6 months of treatment,the VAS of the two groups were lower than before treatment(P<0.05),the VAS of the observation group was higher than that of the control group at 1 month after treatment,and the VAS of the observation group was lower than that of the control group at 3 months and 6 months after treatment,the differences were statistically significant(P<0.05).The ODI of the observation group at 3 and 6 months after treatment was significantly lower than that before treatment(P<0.05).The ODI of the observation group at 3 and 6 months after treatment was lower than that of the control group,and the difference was statistically significant(P<0.05).No serious complications were found in both two groups.Conclusion PRP in the treatment of LFJS is less effective than steroid and local anesthetics in the early stage,but with the extension of time,the curative effect is better than steroid and local anesthetics,which is worthy of clinical application.

关 键 词：腰椎小关节综合征 腰痛 富血小板血浆疗法 

分 类 号：R681.5[医药卫生—骨科学]