Improving the radiopacity of Fe-Mn biodegradable metals by magnetron-sputtered W-Fe-Mn-C coatings:Application for thinner stents  

作　　者：Samira Ravanbakhsh Carlo Paternoster Gianni Barucca Paolo Mengucci Sofia Gambaro Theophraste Lescot Pascale Chevallier a Marc-Andre Fortin Diego Mantovani 

机构地区：[1]Laboratory for Biomaterials and Bioengineering,Canada Research Chair I in Biomaterials and Bioengineering for the Innovation in Surgery,Department of Min-Met-Materials Engineering,Research Center of CHU de Quebec,Division of Regenerative Medicine,Laval University,Quebec City,Quebec G1V 0A6,Canada [2]Laboratory for Biomaterials in Imaging(BIM),Axe Medecine Regeneratrice,Centre Hospitalier Universitaire(CHU)de Quebec-Universite Laval,2705,boul.Laurier(T1-61a),Quebec,G1V 4G2,Canada [3]Department of Materials,Environmental Sciences and Urban Planning,Universita Politecnica delle Marche,via Brecce Bianche 12,60131,Ancona,Italy [4]National Research Council,Institute of Condensed Matter Chemistry and Energy,CNR-ICMATE,Via de Marini 6,16149,Genova,Italy [5]Departement de Genie des Mines,de la Metallurgie et des Materiaux,Centre de Recherche sur les Materiaux Avances(CERMA),Universite Laval,Quebec,G1V 0A6,Canada [6]Axe Medecine Regeneratrice,Centre Hospitalier Universitaire(CHU)de Quebec-Universite Laval,2705,boul.Laurier(T1-61a),Quebec,G1V 4G2,Canada

出　　处：《Bioactive Materials》2022年第6期64-70,共7页生物活性材料（英文）

基　　金：partially funded by the Natural Science and Engineering Research Council of Canada(the Fonds de Recherche du Quebec sur les Natures et Technologie);the Canada Foundation for Innovation;the CHU de Quebec Research Center(through the Fonds de Recherche du Quebec sur la Sante).

摘　　要：In this exploratory work,micrometric radiopaque W-Fe-Mn-C coatings were produced by magnetron sputtering plasma deposition,for the first time,with the aim to make very thin Fe-Mn stents trackable by fluoroscopy.The power of Fe-13Mn-1.2C target was kept constant at 400 W while that of W target varied from 100 to 400 W producing three different coatings referred to as P100,P200,P400.The effect of the increased W power on coatings thickness,roughness,structure,corrosion behavior and radiopacity was investigated.The coatings showed a power-dependent thickness and W concentration,different roughness values while a similar and uniform columnar structure.An amorphous phase was detected for both P100 and P200 coatings while γ-Fe,bcc-W and W_(3)C phases found for P400.Moreover,P200 and P400 showed a significantly higher corrosion rate(CR)compared to P100.The presence of W,W_(3)C as well as the Fe amount variation determined two different micro-galvanic corrosion mechanisms significantly changing the CR of coatings,0.26±0.02,59.68±1.21 and 59.06±1.16μm/year for P100,P200 and P400,respectively.Sample P200 with its most uniform morphology,lowest roughness(RMS=3.9±0.4 nm)and good radiopacity(~6%)appeared the most suitable radiopaque biodegradable coating investigated in this study.

关 键 词：Fe-Mn-Based alloys Degradable coatings W-Fe-Mn-C coatings Magnetron sputtering RADIOPACITY Stent fluoroscopy 

分 类 号：R318[医药卫生—生物医学工程]