活性r型含铜含吲哚美辛宫内节育器的临床节育效果观察  

Clinical Observation on the Birth Control Effect of Active r-type Containing Copper and Indomethacin Intrauterine Device

作　　者：童樱 TONG Ying(Sanming Maternal and Child Health Hospital,Sanming 365000,China)

机构地区：[1]三明市妇幼保健院,福建三明365000

出　　处：《中外医学研究》2022年第9期45-48,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:探讨活性r型含铜含吲哚美辛宫内节育器的临床节育效果。方法:纳入2018年8月-2019年7月到三明市妇幼保健院行宫内节育器放置术的女性共计84例为研究对象,按照电脑随机法将入组女性均分为对照组与试验组,其中对照组(42例)采用元宫型节育器,试验组(42例)采用活性r型含铜含吲哚美辛宫内节育器,随访24个月。观察两组置器24个月后的续用率、带器妊娠率及不良反应发生情况。结果:节育器放置术后12、24个月试验组带器妊娠率(0、4.76%)均低于对照组(2.38%、9.52%),但差异无统计学意义(χ^(2)=0.512、0.180,P>0.05)。随访18、24个月,试验组节育器续用率(100%、95.24%)明显高于对照组(85.71%、80.95%),差异有统计学意义(χ^(2)=4.487、4.480,P<0.05)。随访24个月,试验组置器不良反应发生率[4.76%(2/42)]明显较对照组[21.43%(9/42)]低,差异有统计学意义(χ^(2)=5.126,P<0.05)。结论:活性r型含铜含吲哚美辛宫内节育器应用于有避孕需求的女性,不仅可提高节育器续用率与节育效果,还可降低不良反应发生风险,建议推广应用。Objective:To investigate the birth control effect of active r-type containing copper and Indomethacin intrauterine device (IUD).Method:A total of 84 women who undergoing intrauterine device placement in Sanming Maternal and Child Health Hospital from August 2018 to July 2019 were included as research subjects.According to the computer randomization method,the enrolled women were divided into the control group and the experimental group.Among them,the control group (42 cases) used the Yuan Gong-type IUD,and the experimental group (42 cases) used the active r-type containing copper and Indomethacin intrauterine device,followed up for 24 months.The continuation rate,pregnancy rate and adverse reactions of the two groups after 24 months of device placement were observed.Result:Twelve and twenty-four months after IUD placement,the pregnancy rate (0,4.76%) of the experimental group were lower than 2.38% and 9.52% of the control group,but there were no significant differences (χ^(2)=0.512,0.180,P>0.05).Eighteen and twenty-four months after IUD placement,the continuation rate of IUD in the experimental group (100%,95.24%) were significantly higher than 85.71% and 80.95% of the control group,the differences were statistically significant (χ^(2)=4.487,4.480,P<0.05).After 24 months of follow-up,the incidence of adverse reactions in the experimental group[4.76% (2/42)]was significantly lower than 21.43% (9/42) of the control group,and the difference was statistically significant (χ^(2)=5.126,P<0.05).Conclusion:The active r-type containing copper and Indomethacin intrauterine device used in women with contraceptive needs can not only improve the continuation rate of the device and the effect of birth control,but also reduce the risk of adverse reactions.It is recommended to promote its application.

关 键 词：活性r型 吲哚美辛 节育器 节育效果 不良反应 

分 类 号：R169.4[医药卫生—公共卫生与预防医学]