改良式全自动外周动静脉同步换血术应用于新生儿高胆红素血症的疗效  

Effect of Modified Automatic Peripheral Arteriovenous Synchronous Blood Exchange in Neonates with Hyperbilirubinemia

作　　者：林玉珠 王婉婷 苏平 LIN Yuzhu;WANG Wanting;SU Ping(Quanzhou Maternal and Child Health Care Hospital·Children’s Hospital,Quanzhou 362000,China;不详)

机构地区：[1]泉州市妇幼保健院·儿童医院,福建泉州362000

出　　处：《中外医学研究》2022年第9期48-51,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:探讨改良式全自动外周动静脉同步换血术(改良换血术)应用于新生儿高胆红素血症的疗效。方法:选择泉州市妇幼保健院·儿童医院2019年6月-2021年1月收治的84例高胆红素血症新生儿作为研究对象。按随机数字表法将其分为对照组和观察组,各42例。对照组接受常规换血术治疗,观察组接受改良换血术治疗。比较两组换血前,换血后4 h生化及血常规指标,换血中生命体征。记录两组导管堵塞、脱位的发生率。结果:换血后4 h,两组钠离子(Na^(+))、钾离子(K^(+))、钙离子(Ca^(2+))、白细胞(WBC)对比差异均无统计学意义(P>0.05),观察组总胆红素(TBIL)水平低于对照组,血小板(PLT)、血红蛋白(Hb)水平均高于对照组(P<0.05)。两组换血中心率(HR)、呼吸频率(RR)、血氧饱和度(SpO_(2))、舒张压与收缩压对比差异均无统计学意义(P>0.05)。观察组导管堵塞、脱位发生率低于对照组(P<0.05)。结论:改良换血术应用在于新生儿高胆红素血症中,换血时患儿的生命体征稳定,对内环境的影响小,可纠正贫血,降低胆红素水平,并减少换血中导管堵塞、脱位的发生。Objective:To explore the effect of modified automatic peripheral arteriovenous synchronous blood exchange surgery (modified blood exchange surgery) in neonates with hyperbilirubinemia.Method:A total of 84 neonates with hyperbilirubinemia admitted to Quanzhou Maternal and Child Health Care Hospital·Children’s Hospital from June 2019 to January 2021 were selected as the research subjects.According to the random number table method,they were divided into control group and observation group,42 cases in each group.The control group received conventional blood exchange surgery treatment,and the observation group received modified blood exchange surgery treatment.Biochemical and blood routine indexes before and 4 h after blood exchange and vital signs during blood exchange were compared between the two groups.The incidence of blockage and dislocation of catheter in the two groups were recorded.Result:Four hours after blood exchange,there were no significant differences in sodium ion (Na^(+)),potassium ion (K^(+)),calcium ion (Ca^(2+)),white blood cell (WBC) between the two groups (P>0.05),the level of total bilirubin (TBIL) in the observation group was lower than that in the control group,and the levels of platelet (PLT) and hemoglobin (Hb) in the observation group were higher than those in the control group (P<0.05).There were no significant differences in heart rate (HR),respiratory rate (RR),oxygen saturation (SpO_(2)),diastolic blood pressure and systolic blood pressure during blood exchange between the two groups (P>0.05).The incidence of blockage and dislocation of catheter in the observation group was lower than that in the control group (P<0.05).Conclusion:Modified blood exchange surgery is applied in neonatal with hyperbilirubinemia,during blood exchange,the vital signs of the child are stable,the impact on the internal environment is small,anemia can be corrected,the level of bilirubin can be reduced,and the occurrence of catheter blockage and dislocation in blood exchange can be reduced.

关 键 词：改良式全自动外周动静脉同步换血术 新生儿高胆红素血症 生命体征 生化指标 

分 类 号：R722.17[医药卫生—儿科]