高强度聚焦超声在脊柱与骨关节疼痛中的应用  

Advances of high-intensity focused ultrasound on spinal and osteoarticular pain

作　　者：马云龙[1] 宋春雨 李水清[1] 贾东林[1] MA Yunlong;SONG Chunyu;LI Shuiqing;JIA Donglin(Department of Pain,Peking University Third Hospital,Beijing 100191,China;Department of Anesthesiology,Peking University Third Hospital,Beijing 100191,China)

机构地区：[1]北京大学第三医院疼痛科,北京100191 [2]北京大学第三医院麻醉科,北京100191

出　　处：《中国疼痛医学杂志》2022年第4期244-248,共5页Chinese Journal of Pain Medicine

基　　金：国家自然科学基金(81802686)。

摘　　要：高强度聚焦超声(high intensity focused ultrasound, HIFU)是近年来逐渐兴起的一种无创超声治疗技术。MR引导下的HIFU (MR-guided HIFU, MRgHIFU)能实现对病变靶点的精准消融,其兼具的测温功能还可对消融区温度进行实时监测。MRgHIFU的这些优势使其处理病变的同时极大减少了周围组织损伤风险,显现出良好的有效性和安全性。MRgHIFU作为不同疾病状态的一种多模式治疗选择,在肿瘤学、神经系统、整形外科及康复医学等多领域的临床应用和临床前期研究中已有广泛报道。慢性疼痛是增加全球经济与疾病负担的主要病症,脊柱与骨关节疼痛是导致机体功能障碍的重要原因之一。MRgHIFU作为一种重要的非侵袭性治疗方法可能在脊柱与骨关节疼痛的综合治疗中发挥举足轻重的作用,本文对相关研究进展进行综述,以期为脊柱与骨关节疼痛的微创治疗选择提供重要参考。High intensity focused ultrasound(HIFU) is a non-invasive ultrasound treatment technology that has gradually emerged in recent years. MR-guided HIFU(MRgHIFU) can achieve precise ablation of target tissue,and its temperature measurement function can also real-time monitor the temperature of the ablation zone.These advantages of MRgHIFU enable it to treat lesions accurately while greatly reducing the risk of damage to surrounding tissues, showing good effectiveness and safety. MRgHIFU, as a multi-modal treatment option for different disease states, has been widely used in clinical and preclinical studies in many academic fields such as oncology, nervous system, plastic surgery and rehabilitation medicine. Chronic pain is a major contributor to the global economic and disease burden, in which the spinal and osteoarticular pain is one of the important causes of body dysfunction. As an important non-invasive treatment method, MRgHIFU may play a pivotal role in the comprehensive treatment of spinal and osteoarticular pain. This article reviews the relevant research progress.

关 键 词：高强度聚焦超声 核磁引导 脊柱与骨关节疼痛 非侵袭性 

分 类 号：R445.1[医药卫生—影像医学与核医学] R68[医药卫生—诊断学]