影响细胞电泳力谱和旋转谱的因素分析  

Analyses of the Factors Affecting Dielectrophoresisand Electrorotation Spectra

作　　者：张小娣[1] 吴继侠[1] 马晴[1] ZHANG Xiaodi;WU Jixia;MA Qing(College of Physics&Electronic Engineering,Xianyang Normal University,Xianyang 712000,Shaanxi,China)

机构地区：[1]咸阳师范学院物理与电子工程学院,陕西咸阳712000

出　　处：《咸阳师范学院学报》2022年第2期13-16,共4页Journal of Xianyang Normal University

基　　金：教育部产学协同育人项目(201901260024)。

摘　　要：介电泳(DEP)和电旋转(ROT)是研究细胞生物物理特性的主要方法。基于单壳细胞模型,采用生物电磁学方法,给出克劳修斯-莫索蒂因子,并数值分析了细胞的大小、胞外介质介电常数对DEP、ROT因子的影响。结果表明:细胞大小、胞外介质介电常数均影响细胞恒力频率范围、频率范围对应的电泳力大小,以及细胞第一、第二同向旋转和反向旋转的角速度大小、对应阈值频率点。DEP谱和ROT谱反映细胞大小、胞外介电常数的变化。研究结果可作为细胞生物、物理特性的分析依据。The dielectrophoresis(DEP)and electrorotation(ROT)are the key methods for studying the biophysical properties of cells.Based on the single-shell cell model,the Clausius Mossotti factor is given by the bio-electromagnetics methods,and the effects of cell size and permittivity of extracellular medium on DEP and ROT factors were numerically analyzed.The results show that the cell size and the permittivity of extracellular media affect the frequency range,the electrophoretic force of constant dielectrophoresis force and the angular velocity and corresponding threshold frequency points of the first and second co-rotation.DEP and ROT spectra can reflect the changes of cell size and extracellular dielectric constant numerically.The results of this paper can be used as the basis for analyzing the biological and physical characteristics of cells.

关 键 词：介电泳 电旋转 介电常数 

分 类 号：Q68[生物学—生物物理学]