《结核菌素皮肤试验-γ干扰素释放试验两步法的操作技术规范》解读  

Interpretation of the Procedure of tuberculin skin test-interferon-gamma release assay two-step testing

作　　者：何翼君 曹雪芳 高磊[1] HE Yi-jun;CAO Xue-fang;GAO Lei(Institute of Pathogen Biology,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100730,China)

机构地区：[1]中国医学科学院/北京协和医学院病原生物学研究所,北京100730

出　　处：《中国防痨杂志》2022年第5期438-441,共4页Chinese Journal of Antituberculosis

基　　金：中国医学科学院医学与健康科技创新工程项目(2021-I2M-1-037)。

摘　　要：2021年7月9日中国防痨协会发布了《T/CHATA 016-2021结核菌素皮肤试验-γ干扰素释放试验两步法的操作技术规范》团体标准。文件明确了采用结核菌素皮肤试验-γ干扰素释放试验(tuberculin skin test-interferon-gamma release assay,TST-IGRA)两步法进行结核分枝杆菌(Mycobacterium tuberculosis,MTB)感染检测的术语和定义、适用人群、操作流程、结果解读和处置建议等内容,适用于我国各级疾病预防控制机构、结核病定点医疗机构、基层医疗卫生机构、综合医疗机构和其他相关机构。本文就该团体标准的主要内容和执行中的注意事项进行详细解读,作为MTB感染检测技术规范的补充,以便医务人员能更好地将TST-IGRA两步法应用于MTB感染检测实践。Procedure of tuberculin skin test-interferon-gamma release assay two-step testing(T/CHATA 016-2021)is a social organization standard issued by Chinese Antituberculosis Association on July 9th,2021.This document clarifies the related term and definitions,target populations,operation process,interpretation and disposal suggestions of detection of Mycobacterium tuberculosis(MTB)infection by tuberculin skin test-interferon-gamma release assay(TST-IGRA)two-step testing.It is applicable to disease prevention and control institutions at all levels,designated medical institutions for tuberculosis,primary medical institutions,comprehensive medical institutions and other relevant institutions in China.As a supplement to the technical specification of MTB infection detection,this article provided a detailed interpretation of the main content and precautions in the implementation,so that the TST-IGRA two-step method could be better applied to the practice of MTB infection detection by medical staff.

关 键 词：分枝杆菌 结核 感染 皮肤试验 干扰素类 免疫学试验 

分 类 号：R52[医药卫生—内科学] R446.6[医药卫生—临床医学]