中美部分品牌烟草制品TSNA及其前体物的含量和关系  

The correlation between TSNAs content and their precursors content in some tobacco products on Chinese and the United States’ markets

作　　者：周炎[1,2] 史宏志 季辉华[2] 周骏 张杰[3] 白若石[3] 杨惠娟[1] ZHOU Yan;SHI Hongzhi;JI Huihua;ZHOU Jun;ZHANG Jie;BAI Ruoshi;YANG Huijuan(Tobacco Harm Reduction Research Center,College of Tobacco Science,Henan Agricultural University,Zhengzhou 450002,China;Kentucky Tobacco Research&Development Center,University of Kentucky,1401 University Drive.Lexington,Kentucky,40503,the United States;Shanghai Tobacco Group Beijing Cigarette Factory,Tongzhou District,Beijing 100024,China)

机构地区：[1]河南农业大学烟草学院/烟草农业减害研究中心,郑州市 [2]美国肯塔基大学肯塔基烟草研究与发展中心,美国肯塔基州1401号40503 [3]上海烟草集团北京卷烟厂,北京市通州区万100024

出　　处：《中国烟草学报》2022年第2期42-49,共8页Acta Tabacaria Sinica

基　　金：四川省烟草公司科技项目(SCYC201915);CSC国家留学基金委2018公派硕士项目(学号201808410388)。

摘　　要：【目的】初步了解中美市售部分烟草制品TSNA及其前体物的含量及关系,为雪茄安全性研究提供参考。【方法】收集了中美市售卷烟及雪茄共37款烟草制品,对其TSNA以及其前体物含量进行测定,并进行相关分析。【结果】(1)烟碱转化率美国雪茄最高,平均5.50%,中式卷烟样本烟碱转化率最低,平均为2.83%,且与美国雪茄样本存在显著差异。(2)硝酸盐含量美国雪茄最高,平均为11.69mg/g,中国卷烟最低,平均仅为0.75mg/g,美国卷烟硝酸盐含量约为中国卷烟的7.7倍。(3)TSNA含量:雪茄>卷烟,中、美雪茄总TSNA平均值分别为20.62、19.86μg/g,中国卷烟含量最低,平均仅为0.25μg/g,美国卷烟含量约为中国的18倍。(4)烟碱转化率与硝酸盐含量呈极显著正相关。硝酸盐含量与NNK含量呈显著正相关,与其他TSNA含量呈极显著正相关。亚硝酸盐含量与NAB、NNK和总TSNA含量的相关性极显著。新烟草碱含量与所有TSNA含量均呈极显著负相关。【结论】硝酸盐含量、亚硝酸盐含量及烟碱转化率与TSNA含量相关性较强,雪茄类烟草制品安全性仍有待提高。[Backgrounds] A preliminary understanding of the relationship of TSNAs content and their precursors content in some tobacco products sold in China and the United States will provide references for cigar safety research. [Methods] A total of 37 tobacco products,including cigarettes and cigars on the market in China and the United States were collected, and the contents of TSNAs and their precursors were determined and analyzed. [Results](1) The nicotine conversion rate of American cigars is the highest, with an average of 5.50%;in contrast, the nicotine conversion rate of Chinese cigarette samples is the lowest, with an average of 2.83%, indicating a very significant difference.(2) The nitrate content of American cigars is the highest, with an average of 11.69 mg/g, while that of Chinese cigarettes is the lowest, with an average of 0.75 mg/g. The nitrate content of American cigarettes is about 7.7 times of that of Chinese cigarettes.(3) TSNA content of cigars is greater than cigarettes, the average amount of total TSNA of American and Chinese cigars are 20.62 and 19.86 μg/g,respectively;Chinese cigarettes have the lowest TSNA content, which is only 0.25 μg/g, and American cigarettes contain approximately 18times that of Chinese cigarettes.(4) Nicotine conversion rate and nitrate content have a very significant positive correlation. Nitrate content has a significant positive correlation with NNK content, and a very significant positive correlation with other TSNAs content. The correlation between nitrite content and the contents of NAB, NNK and total TSNAs is extremely significant. Anatabine content has a very significant negative correlation with all TSNAs contents. [Conclusion] The contents of nitrate, nitrite and PNC has a strong correlation with the content of TSNA, and the safety of cigar tobacco products still needs to be improved.

关 键 词：卷烟 雪茄 烟草制品 TSNA 硝酸盐 烟碱 烟碱转化率 

分 类 号：TS411[农业科学—烟草工业]