欣母沛联合米索前列醇治疗产后出血的临床效果分析  

Analysis of the Clinical Effect of Xinmupei Combined with Misoprostol in the Treatment of Postpartum Hemorrhage

作　　者：熊国海[1] XIONG Guohai(Department of Obstetrics and Gynecology,Yancheng Third People's Hospital,Yancheng School of Clinical Medicine,Nanjing Medical University,Yancheng,Jiangsu Province,224000 China)

机构地区：[1]南京医科大学盐城临床医学院盐城市第三人民医院妇产科,江苏盐城224000

出　　处：《系统医学》2022年第2期159-162,共4页Systems Medicine

摘　　要：目的探析产后出血产妇接受欣母沛联合米索前列醇治疗的临床效果。方法该研究于2018年1月—2021年7月对该科室收治的60例产后出血产妇进行临床研究,结合不同治疗方法对其随机分组,接受米索前列醇治疗的30例产妇为对照组,接受欣母沛联合米索前列醇治疗的30例产妇为观察组。记录产妇不同时段出血量,观察产妇临床疗效、止血时间、术后血红蛋白指标差异,判断产妇用药后安全性。结果经联合诊治,观察组分娩时、2、4、24 h出血量为(174.67±5.62)、(201.31±9.67)、(243.65±7.86)、(251.24±5.62)mL,均少于对照组,差异有统计学意义(P<0.05);观察组产妇治疗总有效率(83.33%)明显高于对照组,差异有统计学意义(χ^(2)=4.022,P<0.05);观察组经治疗,产妇止血时间(27.36±1.09)min、术后血红蛋白(9.78±2.43)g/L,和对照组指标相比,差异有统计学意义(P<0.05);经治疗,观察组发生恶心呕吐、头痛、血压升高等不良反应产妇5例,发生率为16.67%,低于对照组,差异有统计学意义(χ^(2)=5.079,P<0.05)。结论产后出血产妇接受欣母沛联合米索前列醇治疗,大幅减少了产妇的产后出血量,缩短了产妇的止血时间,治疗安全性明显高于米索前列醇单独治疗。Objective To explore the clinical effect of treatment with Xinmupei combined with misoprostol in women with postpartum hemorrhage.Methods This study conducted a clinical study on 60 women with postpartum hemorrhage admitted to the department from January 2018 to July 2021,and randomized them with different treatment methods.30 women who received misoprostol were used as the control group,30 women of parturients who received the treatment of Xinmupei combined with misoprostol were the observation group.The bleeding volume of the parturient was recorded at different times,and the clinical efficacy,hemostasis time,and the difference in hemoglobin index after the operation were observed;the safety of the parturient after medication was judged.Results After combined diagnosis and treatment,the bleeding volume of the observation group at delivery,2 h,4 h,and 24 h were(174.67±5.62)mL,(201.31±9.67)mL,(243.65±7.86)mL,(251.24±5.62)mL,all less than the control group,the difference was statistically significant(P<0.05);the total effective rate of the observation group(83.33%)was significantly higher than that of the control group,the difference was statistically significant(χ^(2)=4.022,P<0.05).After treatment,the observation group had a hemostatic time(27.36±1.09)min and postoperative hemoglobin(9.78±2.43)g/L,compared with the control group,the difference was statistically significant(P<0.05).After treatment,5 parturients in the observation group had adverse reactions such as nausea,vomiting,headache,and elevated blood pressure,and the incidence was 16.67%,which was lower than that of the control group,the difference was statistically significant(χ^(2)=5.079,P<0.05).Conclusion The treatment of Xinmupei with postpartum hemorrhage combined with Misoprostol significantly reduces the amount of postpartum hemorrhage of the puerpera and shortens the time of hemostasis for the puerpera.The safety of treatment is significantly higher than that of misoprostol alone.

关 键 词：产后出血 欣母沛 米索前列醇 凝血功能 宫缩乏力 

分 类 号：R71[医药卫生—妇产科学]