肉桂酸制备工艺研究及在有机化学实验教学中的应用  

Study on Synthesis of Cinnamic Acid and Its Application in the Organic Chemistry Experiment Teaching

作　　者：刘丽敏[1] 吉小利[1] 石建军[1] 邵小娜 张艳红[1] LIU Li-min;JI Xiao-li;SHI Jian-jun;SHAO Xiao-na;ZHANG Yan-hong(School of Chemical Engineering,Anhui University of Science and Technology,Huainan 232001,China;College of Chemistry and Materials Engineering,Huaihua University,Huaihua 418000,China)

机构地区：[1]安徽理工大学化学工程学院,安徽淮南232001 [2]怀化学院化学与材料工程学院,湖南怀化418000

出　　处：《安徽化工》2022年第2期64-66,共3页Anhui Chemical Industry

基　　金：安徽省教育厅质量工程重点项目,争创一流本科专业背景下应用化学专业教学体系改革(2019jyxm0163)。

摘　　要：实验教学中肉桂酸的制备通常采用Perkin反应由苯甲醛和乙酸酐为原料制得,其在基础化学实验教学中占有比较重要的一环。然而在教学实践中,现有的制备方法耗时长且学生很难得到产品。讨论了反应温度、反应时间、反应物摩尔比和催化剂用量对肉桂酸产率的影响,确定了最佳反应条件。将此反应条件应用到教学实践中,反应效率明显提高,实验教学时间明显缩短,且每一组同学都能得到纯度较高的产品。In experimental teaching, the preparation of cinnamic acid is usually made from benzaldehyde and acetic anhydride by Perkin reaction, which plays an important role in basic chemistry experimental teaching. However, in classrom practice, existing preparation methods are time-consuming and difficult for students to access. The effects of reaction temperature, reaction time, molar ratio of reactants and amount of catalyst on the yield of cinnamic acid were discussed, and the optimum reaction conditions were determined. The experimental teaching under this reaction condition can improve the reaction efficiency, shorten the experimental teaching time obviously, and each group of students can get the product with high purity.

关 键 词：肉桂酸 PERKIN反应 产率 

分 类 号：G642[文化科学—高等教育学]