阿司匹林急诊治疗血栓性脑梗死的效果及对神经功能的影响  

Effect of Aspirin in the Emergency Treatment of Thrombotic Cerebral Infarction and Its Influence on Nerve Function

作　　者：张洪林[1] 韩建 ZHANG Honglin;HAN Jian(Emergency Department,Longyan Second Hospital,Longyan,Fujian Province,364000 China)

机构地区：[1]龙岩市第二医院急诊科,福建龙岩364000

出　　处：《中外医疗》2022年第3期17-20,共4页China & Foreign Medical Treatment

基　　金：龙岩市科技计划项目(2018LYF5015)。

摘　　要：目的研究阿司匹林急诊治疗血栓性脑梗死的效果及对神经功能的影响。方法便利选取该院2019年6月—2020年5月急诊收治的120例血栓性脑梗死患者,根据就诊序号分为研究组与对照组,每组60例。对照组应用常规治疗方式,研究组在此基础上应用阿司匹林进行治疗,比较两组治疗效果、神经功能评分以及不良反应发生率。结果研究组治疗总有效率(91.67%)明显高于对照组(83.33%),差异有统计学意义(χ^(2)=5.925,P=0.015)。两组患者治疗前神经功能评分差异无统计学意义(P>0.05),治疗后研究组神经功能(10.42±1.26)分明显低于对照组(18.57±2.04)分,差异有统计学意义(t=26.329,P<0.001)。研究组不良反应发生率(5.00%)明显低于对照组(18.33%),差异有统计学意义(χ^(2)=5.175,P=0.023)。研究组神经功能恢复正常范围内时间(11.08±3.16)d明显短于对照组(16.36±3.27)d,差异有统计学意义(t=8.994,P<0.05)。治疗后,研究组PT指标为(8.24±0.79)s、APTT指标为(16.32±5.22)s、Fib指标为(2.74±0.55)g/L,优于对照组(9.46±0.65)s、(20.62±6.14)s、(3.45±0.06)g/L,差异有统计学意义(t=9.237、4.133、9.940,P<0.05)。结论急诊治疗的血栓性脑梗死患者应用阿司匹林治疗,可明显提升治疗效果,改善患者神经功能,降低不良反应发生率,缩短神经功能恢复时间,更利于身体的恢复,具有临床推广应用价值。Objective To study the effect of aspirin on the emergency treatment of thrombotic cerebral infarction and its influence on nerve function.Methods Conveniently selected 120 patients with thrombotic cerebral infarction admitted to the emergency department of the hospital from June 2019 to May 2020,and divided them into study group and control group,with 60 cases in each group.The control group was treated with conventional treatment,and thestudy group was treated with aspirin on this basis.The treatment effect,neurological function score and the incidence of adverse reactions were compared between the two groups.Results The total effective rate of the study group(91.67%)was significantly higher than that of the control group(83.33%),the difference was statistically significant(χ^(2)=5.925,P=0.015).There was no statistically significant difference in neurological function scores between the two groups before treatment(P>0.05).After treatment,the neurological function(10.42±1.26)points of the study group was significantly lower than that of the control group(18.57±2.04)points,the difference was statistically significant(t=26.329,P<0.001).The incidence of adverse reactions in thestudy group(5.00%)was significantly lower than that in the control group(18.33%),the difference was statistically significant(χ^(2)=5.175,P=0.023).After treatment,the time for the neurological function to recover within the normal range of thestudy group(11.08±3.16)d was significantly shorter than that of the control group(16.36±3.27)d,the difference was statistically significant(t=8.994,P<0.05).The PT index of thestudy group was(8.24±0.79)s,the APTT index was(16.32±5.22)s,and the Fib index was(2.74±0.55)g/L,better than the control group(9.46±0.65)s,(20.62±6.14)s,(3.45±0.06)g/L,the difference was statistically significant(t=9.237,4.133,9.940,P<0.05).Conclusion The application of aspirin in patients with thrombotic cerebral infarction treated in emergency can significantly improve the treatment effect,improve patients'neurological f

关 键 词：阿司匹林 急诊 血栓性脑梗死 临床疗效 神经功能评分 

分 类 号：R4[医药卫生—临床医学]