切割球囊成形术应用于冠状动脉支架内再狭窄的疗效探讨  

The Effect of Cutting Balloon Angioplasty in Coronary Stent Restenosis

作　　者：刘子龙 LIU Zilong(Department of Cardiology,Beijing Changping Hospital,Beijing,102200 China)

机构地区：[1]北京市昌平医院心内科,北京102200

出　　处：《中外医疗》2022年第3期41-44,共4页China & Foreign Medical Treatment

摘　　要：目的探讨切割球囊成形术治疗冠状动脉支架内再狭窄的临床疗效。方法随机选取2017年6月—2020年6月期间该院80例冠状动脉支架内再狭窄患者,根据随机数字法将其分为对照组(普通球囊成形术)和观察组(切割球囊成形术),每组40例。观察和比较两组患者术后即刻、术后6个月、术后12个月狭窄血管最小直径、靶血管狭窄程度,以及术后3个月、术后6个月、术后12个月管腔丢失情况,以及术后随访12个月再狭窄发生率。结果与对照组相比,观察组术后狭窄血管最小直径明显增大[术后即刻(3.3±0.4)mm vs(2.6±0.4)mm,术后6个月(3.0±0.3)mm vs(2.2±0.3)mm,术后12个月(2.9±0.4)mm vs(2.1±0.4)mm],差异有统计学意义(t=7.826、11.926、8.944,P<0.05);靶血管狭窄程度得到了明显改善[术后即刻(7.6±1.8)%vs(10.3±2.2)%,术后6个月(9.4±1.5)%vs(12.3±3.4)%,术后12个月(10.3±2.1)%vs(14.2±2.2)%],差异有统计学意义(t=6.007、4.935、8.110,P<0.05);管腔丢失明显减少[术后3个月(0.1±0.0)mm vs(0.2±0.1)mm,术后6个月(0.2±0.1)mm vs(0.4±0.1)mm,术后12个月(0.2±0.1)mm vs(0.5±0.2)mm],差异有统计学意义(t=6.325、8.944、8.485,P<0.05);术后随访12个月,再狭窄发生率显著降低(12.5%vs 40.0%),差异有统计学意义(χ^(2)=7.813,P<0.05)。结论切割球囊成形术不仅能够提高冠状动脉支架内再狭窄治疗的临床疗效,还能降低术后再狭窄的发生率,值得临床广泛推广。Objective To explore the clinical efficacy of cutting balloon angioplasty in the treatment of coronary artery restenosis.Methods Randomly selected 80 patients with coronary artery restenosis in the hospital from June 2017 to June 2020.According to the random number method,they were divided into a control group(ordinary balloon angioplasty)and an observation group(cutting balloon angioplasty),with 40 cases in each group.Observed and compared the minimum diameter of the stenosis vessel and the degree of target vessel stenosis after operation,6 months after operation,and 12 months after operation.And the loss of lumen at 3 months after surgery,6 months after surgery,and 12 months after surgery and the incidence of restenosis after 12 months of follow-up.Results Compared with the control group,the minimum diameter of postoperative stenotic vessels in the observation group increased significantly[immediately after operation(3.3±0.4)mm vs(2.6±0.4)mm,6 months after operation(3.0±0.3)mm vs(2.2±0.3)mm,12 months after operation(2.9±0.4)mm vs(2.1±0.4)mm],and the difference was statistically significant(t=7.826,11.926,8.944,P<0.05);the degree of target vessel stenosis was significantly improved[(7.6±1.8)%vs(10.3±2.2)%immediately after operation,(9.4±1.5)%vs(12.3±3.4)%,6 months after operation,and(10.3±2.1)%vs(14.2±2.2)%12 months after operation].The difference was statistically significant(t=6.007,4.935,8.110,P<0.05);lumen loss was significantly reduced[3 months after operation(0.1±0.0)mm vs(0.2±0.1)mm,6 months after operation(0.2±0.1)mm vs(0.4±0.1)mm,12 months after operation(0.2±0.1)mm vs(0.5±0.2)mm],the difference was statistically significant(t=6.325,8.944,8.485,P<0.05);after 12 months of follow-up,the incidence of restenosis decreased significantly(12.5%vs 40.0%),and the difference was statistically significant(χ^(2)=7.813,P<0.05).Conclusion Cutting balloon angioplasty can not only improve the clinical efficacy of coronary stent restenosis treatment,but also reduce the incidence of postoperative reste

关 键 词：切割球囊成形术 冠状动脉支架内再狭窄 狭窄血管最小直径 靶血管狭窄程度 管腔丢失 

分 类 号：R54[医药卫生—心血管疾病]