超声引导下前锯肌阻滞在肺癌根治术患者中的应用效果及对认知功能的影响  

Application Effect of Anterior Serratus Block Guided by Ultrasound in Patients with Radical Resection of Lung Cancer and Influence for the Cognitive Function

作　　者：李其金[1] 钟丽明 黎铨初 LI Qijin;ZHONG Liming;LI Quanchu(The People’s Hospital of Nanhai District,Guangdong Province,Foshan 528200,China;不详)

机构地区：[1]广东省佛山市南海区人民医院,广东佛山528200 [2]佛山市南海区卫生职业技术学校

出　　处：《中国医学创新》2022年第12期141-144,共4页Medical Innovation of China

基　　金：2018年佛山市自筹经费类科技计划项目(2018AB001912)。

摘　　要：目的:探究超声引导下前锯肌阻滞在肺癌根治术患者中的应用效果及对认知功能的影响。方法:选取2020年1-12月佛山市南海区人民医院的86例肺癌根治术患者为研究对象,根据随机数字表法将其分为对照组和观察组,每组43例。对照组行单纯全麻,观察组行超声引导下前锯肌阻滞。比较两组术后不同时间静息及咳嗽状态时的疼痛程度(VAS评分)、认知功能(MMSE量表)、术前及术后6、12、24 h的炎症因子(血清CRP、PCT及IL-6)。结果:术后2、6、12、24 h,观察组静息状态时的疼痛程度均显著低于对照组,差异均有统计学意义(P<0.05)。术后2、6、12、24 h,观察组咳嗽状态时的疼痛程度均显著低于对照组,差异均有统计学意义(P<0.05)。术后2、7 d,两组MMSE量表评分比较,差异均无统计学意义(P>0.05)。术前,两组的CRP、PCT、IL-6水平比较,差异均无统计学意义(P>0.05);术后6、12、24 h,观察组的CRP、PCT、IL-6水平均显著低于对照组,差异均有统计学意义(P<0.05)。结论:超声引导下前锯肌阻滞在肺癌根治术患者中的应用效果较好,可有效控制疼痛及炎症因子的表达,并未对认知功能造成较大的影响,因此在肺癌根治术患者中的应用价值较高。Objective:To explore the application effect of anterior serratus block guided by ultrasound in patients with radical resection of lung cancer and its effect on cognitive function.Method:A total of 86 patients undergoing radical lung cancer surgery in People’s Hospital of Nanhai District of Foshan City from January to December 2020 were selected as the research objects and divided into control group and observation group according to random number table method,43 cases in each group.The control group received simple general anesthesia,and the observation group received anterior serratus block guided by ultrasound.The pain degree (VAS score),cognitive function (MMSE scale),inflammatory factors (serum CRP,PCT and IL-6) before and at 6,12 and 24 h after operation were compared between the two groups.Result:At 2,6,12 and 24 h postoperatively,pain degree in the observation group were significantly lower than those in the control group at rest,the differences were statistically significant (P<0.05).At 2,6,12 and 24 h after operation,pain degree in the observation group were significantly lower than those in the control group,the differences were statistically significant (P<0.05).There were no significant differences in MMSE scores between the two groups at 2 and 7 d after surgery (P>0.05).Before surgery,there were no significant differences in CRP,PCT,IL-6 between the two groups (P>0.05);6,12,24 h after surgery,the CRP,PCT,IL-6 in the observation group were significantly lower than those in the control group,the differences were statistically significant (P<0.05).Conclusion:The application effect of anterior serratus block guided by ultrasound in patients undergoing radical resection of lung cancer is good.It can effectively control the expression of pain and inflammatory factors,and has no great impact on cognitive function.Therefore,it has high application value in patients undergoing radical resection of lung cancer.

关 键 词：超声引导下前锯肌阻滞 肺癌根治术 炎症因子 认知功能 

分 类 号：R614[医药卫生—麻醉学] R734.2[医药卫生—外科学]