早产儿喂养不耐受的相关危险因素分析  

Analysis of Related Risk Factors of Feeding Intolerance in Premature Infants

作　　者：郭晶[1] 肖冬素 李金花[1] 吉娟萍 吴鹏琴 GUO Jing;XIAO Dongsu;LI Jinhua;JI Juanping;WU Pengqin(Ganzhou People’s Hospital,Jiangxi Province,Ganzhou 341000,China;不详)

机构地区：[1]江西省赣州市人民医院,江西赣州341000

出　　处：《中国医学创新》2022年第8期165-168,共4页Medical Innovation of China

摘　　要：目的:探讨早产儿喂养不耐受(FI)的相关危险因素。方法:回顾性分析2020年1月-2021年2月赣州市人民医院新生儿重症监护室收治的84例早产儿临床资料,分析早产儿FI的相关危险因素。结果:84例早产儿中出现喂养不耐受28例(33.33%)。是否发生喂养不耐受早产儿的胎龄、开奶时间、宫内窘迫、新生儿坏死性小肠结肠炎情况比较,差异均有统计学意义(P<0.05)。是否发生喂养不耐受早产儿的性别、出生体质量、剖宫产、胎膜早破、宫内感染、新生儿呼吸窘迫、支气管发育不良、输血、早产儿贫血、新生儿肺炎、喂养方式比较,差异均无统计学意义(P>0.05)。多因素分析显示,胎龄<32周[β=2.787,OR=16.228,95%CI(4.339,60.697)]、开奶时间≥72 h[β=1.165,OR=3.206,95%CI(1.063,9.670)]、宫内窘迫[β=1.406,OR=4.080,95%CI(1.191,13.975)]、新生儿坏死性小肠结肠炎[β=2.481,OR=11.957,95%CI(1.323,108.070)]是早产儿FI的高危因素。结论:早产儿FI的发生与胎龄、开奶时间、宫内窘迫、新生儿坏死性小肠结肠炎有关,针对各危险因素制定相应的干预措施,有望减少FI发生。Objective:To investigate the related risk factors of feeding intolerance (FI) in preterm infants.Method:The clinical data of 84 premature infants admitted to the Neonatal Intensive Care Unit of Ganzhou People’s Hospital from January 2020 to February 2021 were retrospectively analyzed,and the related risk factors for FI in premature infants were analyzed.Result:Feeding intolerance occurred in 28 of the 84 premature infants (33.33%).There were statistically significant differences in the gestational age,feeding time,intrauterine distress,and neonatal necrotizing enterocolitis of preterm infants with or without feeding intolerance (P<0.05).There were no significant differences in sex,birth weight,cesarean section,premature rupture of membranes,intrauterine infection,neonatal respiratory distress,bronchial dysplasia,blood transfusion,anemia of prematurity,neonatal pneumonia,feeding methods of preterm infants with or without feeding intolerance (P>0.05).Multivariate analysis showed that the gestational age was <32 weeks[β=2.787,OR=16.228,95%CI (4.339,60.697)],and feeding time ≥72 h was[β=1.165,OR=3.206,95%CI (1.063,9.670)],intrauterine distress[β=1.406,OR=4.080,95%CI (1.191,13.975)],neonatal necrotizing enterocolitis[β=2.481,OR=11.957,95%CI (1.323,108.070)]were high risk factors for FI in preterm infants.Conclusion:The occurrence of FI in preterm infants is related to gestational age,feeding time,intrauterine distress,and neonatal necrotizing enterocolitis,corresponding intervention measures for each risk factor are expected to reduce the occurrence of FI.

关 键 词：喂养不耐受 早产儿 开奶时间 

分 类 号：R722.6[医药卫生—儿科]