机构地区:[1]昆明市儿童医院眼科,云南昆明650024 [2]昆明医科大学公共卫生学院,云南昆明650500 [3]云南省第一人民医院眼科,云南昆明650032
出 处:《昆明理工大学学报(自然科学版)》2022年第2期98-104,共7页Journal of Kunming University of Science and Technology(Natural Science)
基 金:云南省眼底病研究中心项目(2017NS260);井上真专家工作站项目(202005AF150030)。
摘 要:为了解新生儿眼底筛查异常的分布情况及其主要影响因素,探讨影响新生儿眼病接受筛查和治疗的更多社会因素,为儿童眼病的预防和控制提供科学依据.于2019年3月—2021年7月,收集云南省8 700名新生儿眼底筛查的相关数据,采用χ^(2)检验和多因素logistic回归模型分析新生儿眼底筛查异常状况及其影响因素.8 700名新生儿眼底筛查异常率为12.26%(1 067/8 700),单因素分析结果显示,母亲文化程度、参加的医疗保险、产后是否使用机械辅助呼吸、产后持续吸氧时间、是否发生新生儿感染、是否患新生儿肺透明膜病、出生体重、分娩方式、孕周的新生儿眼底筛查异常率差异均有统计学意义(P值均<0.05);多因素logistic回归模型分析结果显示,学历为初中(OR=1.715,95%CI=1.248-2.357)、高中(专科、技校)(OR=2.265,95%CI=1.785-2.872)和大专(本科及以上)(OR=2.165,95%CI=1.775-2.640),出生体重≥4 000 (OR=1.401,95%CI=1.026-1.912),顺产(OR=5.344,95%CI=4.207-6.788)均是新生儿眼底筛查异常的影响因素.新生儿眼底筛查对于新生儿的生命健康及其今后的生活质量至关重要,应有针对性地对其父母进行健康教育,加大新生儿眼底筛查的力度,加强应对新生儿眼底筛查异常的治疗和预防能力,为推行新生儿眼底筛查提高可行性.This article aims to understand the distribution of abnormal neonatal fundus screening and its main influencing factors,and explores more social factors that affect the screening and treatment of neonatal eye diseases,so as to provide scientific basis for the prevention and control of children’s eye diseases.From March,2019 to July,2021,the related data of 8 700 newborns’ fundus screening in Yunnan Province were collected,and the abnormal situation of neonatal fundus screening and its influencing factors were analyzed by χ^(2) test and multivariate logistic regression model.The abnormal rate of fundus screening among 8 700 newborns was 12.26%(1 067/8 700).The results of single factor analysis showed that there were statistically significant differences in maternal education,medical insurance,whether to use mechanical assisted breathing after delivery,continuous oxygen inhalation time after delivery,whether to have neonatal infection,whether to have hyaline membrane disease of newborn,birth weight,mode of delivery and abnormal rate of fundus screening at gestational age(P values were all less than 0.05).The results of multivariate logistic regression model analysis show that the educational background is junior high school(OR =1.715,95% CI=1.248-2.357),senior high school(junior college and technical school)(OR= 2.265,95% CI=1.785-2.872) and junior college(bachelor degree or above)(OR= 2.165,95% CI =1.775-2.640).Birth weight > 4 000(OR=1.401,95%CI=1.026-1.912) and natural delivery(OR=5.344,95%CI=4.207-6.788) are the influencing factors of abnormal neonatal fundus screening.Neonatal fundus screening is very important for newborn’s life and health and their future quality of life.It is necessary to carry out targeted health education for their parents,increase the intensity of neonatal fundus screening,strengthen the treatment and prevention ability to deal with abnormal neonatal fundus screening,and improve the feasibility of neonatal fundus screening.
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