核素心肌显像在冠状动脉慢性完全闭塞临床诊疗中的应用价值  

Application Value of Radionuclide Myocardial Imaging in Clinical Diagnosis and Treatment of Coronary Chronic Total Occlusion

作　　者：马兴鸿 汪蕾 方纬 MA Xinghong;WANG Lei;FANG Wei(Department of Nuclear Medicine,Fuwai Hospital,Chinese Academy of Medical Sciences,Beijing 100037,China)

机构地区：[1]中国医学科学院阜外医院核医学科,北京100037

出　　处：《心血管病学进展》2022年第4期313-317,共5页Advances in Cardiovascular Diseases

摘　　要：冠状动脉慢性完全闭塞(CTO)较为常见且预后不良。虽然CTO患者经皮冠状动脉介入治疗(PCI)的成功率已较以往明显提高,但PCI的治疗决策仍是有争议的问题。研究表明:CTO血管支配区域是否存在心肌缺血和存活心肌可能与从PCI中获益的CTO患者的筛选及其预后密切相关。现综述应用核素心肌灌注显像和心肌代谢显像分别评估CTO病变血管支配区域的心肌缺血和存活心肌的相关研究,初步探讨这两种核素显像技术在CTO病变治疗决策和预后评估方面的应用价值。Coronary chronic total occlusion(CTO)is common and has a negative prognosis.Although the success rate of percutaneous coronary intervention(PCI)for CTO patients has been significantly improved,yet the therapeutic strategy of PCI is controversial.Research has shown that whether myocardial ischaemia and viable myocardium was present or not in the territory dominated by CTO vessel probably associated with patient selection of PCI and prognosis.This article reviewed related studies of application of radionuclide myocardial perfusion imaging and myocardial metabolism imaging to assess myocardial ischaemia and viable myocardium in the territory dominated by CTO vessel,and preliminarily explored the application value of these two radionuclide imaging techniques in CTO lesion therapeutic strategy and prognostic evaluation.

关 键 词：冠状动脉慢性完全闭塞 心肌灌注显像 心肌代谢显像 心肌缺血 心肌存活 经皮冠状动脉介入治疗 

分 类 号：R54[医药卫生—心血管疾病]