肺活检技术联合快速现场细胞学评价在肺部阴影诊断中的价值  

The value of lung biopsy combined with cytological rapid on-site evaluation in the diagnosis of lung shadowing

作　　者：王国庆[1] 冯田 胡爱侠[2] Wang Guoqing;Feng Tian;Hu Aixia(Department of Pathology,Jiaozuo People's Hospital,Jiaozuo Henan 454002,China;Department of Pathology,Henan Provincial People's Hospital,Zhengzhou 450000,China)

机构地区：[1]焦作市人民医院病理科,河南焦作454002 [2]河南省人民医院病理科,郑州450000

出　　处：《保健医学研究与实践》2022年第4期60-62,共3页Health Medicine Research and Practice

基　　金：河南省重大科研专项项目(161100311400)。

摘　　要：目的分析肺活检技术联合快速现场细胞学评价(C-ROSE)在肺部阴影诊断中的价值。方法选取2019年1月—2021年3月焦作市某医院收治的168例肺部阴影患者为研究对象。所有患者均行超声引导下经皮穿刺肺活检,并根据是否采用C-ROSE将其分为C-ROSE组(84例)和常规细胞学检查组(84例),以组织学病理结果为金标准,比较2组患者肺部阴影诊断结果以及穿刺次数、手术操作时间、二次穿刺活检阳性率、穿刺后并发症发生率。结果组织学病理结果显示,C-ROSE组患者中恶性肿瘤患者70例,良性病变患者14例;常规细胞学检查组患者中恶性肿瘤患者68例,良性病变患者16例。C-ROSE组患者诊断肺部阴影的灵敏度为94.29%、特异度为78.57%、准确率为91.67%,Kappa值为0.708,与金标准的一致性较高。常规细胞学检查组患者诊断肺部阴影的灵敏度为79.41%、特异度为75.00%、准确率为78.57%,Kappa值为0.439,与金标准的一致性中等。C-ROSE组患者的穿刺次数、二次穿刺活检阳性率均低于常规细胞学检查组,差异均有统计学意义(P<0.05);C-ROSE组患者的手术操作时间长于常规细胞学检查组,差异有统计学意义(P<0.05)。C-ROSE组患者穿刺后并发症发生率为4.76%,低于常规细胞学检查组的14.29%,差异有统计学意义(χ^(2)=4.421,P=0.035)。结论肺活检技术联合C-ROSE可提高肺部阴影患者的诊断效能,降低穿刺次数、二次穿刺活检阳性率及穿刺后并发症发生率。Objective To analyze the value of lung biopsy combined with cytological rapid on-site evaluation(C-ROSE)in the diagnosis of lung shadowing.Methods One hundred and sixty-eight patients with lung shado-wing admitted to a hospital in Jiaozuo from January 2019 to March 2021 were selected for the study.All patients underwent ultrasound-guided percutaneous puncture lung biopsy,and they were divided into the C-ROSE group(84 cases)and the conventional cytology group(84 cases)according to whether C-ROSE was used,and the his-tological pathology results were used as the gold standard to compare the diagnostic results of lung shadowing as well as the number of punctures,surgical operation time,secondary puncture biopsy rate,and complication rate in the 2 groups.Results The results of histological pathology showed that there were 70 patients with malignant tumors and 14 patients with benign lesions in the C-ROSE group,and 68 patients with malignant tumors and 16 patients with benign lesions in the conventional cytology group.The sensitivity of patients in the C-ROSE group for the diagnosis of lung shadowing was 94.29%,the specificity was 78.57%,the accuracy was 91.67%,and the Kappa value was 0.708,with high agreement with the gold standard.The sensitivity of patients in the con-ventional cytology group for the diagnosis of lung shadowing was 79.41%,the specificity was 75.00%,the accu-racy was 78.57%,and the Kappa value was 0.439,which were in moderate agreement with the gold standard.The number of punctures and the rate of secondary puncture biopsies in the C-ROSE group were lower than those in the conventional cytology group,and the differences were statistically significant(P<0.05);the operation time in the C-ROSE group was longer than that in the conventional cytology group,and the difference was statis-tically significant(P<0.05).The complication rate of patients in C-ROSE group during treatment was 4.76%,which was lower than that of 14.29%in conventional cytology group,and the difference was statistically signifi-cant(χ

关 键 词：肺活检技术 快速现场细胞学评价 肺部阴影 

分 类 号：R563[医药卫生—呼吸系统]