E超弹性成像评估肝癌非肿瘤区域肝质纤维化的临床价值  

E-ultrasound imaging in evaluating the clinical value of hepatic fibrosis in non-tumor areas of liver cancer

作　　者：伍华亮 朱江[1] 梁义娇[1] 张水连 李晓媛 Wu Hualiang;Zhu Jiang;Liang Yijiao;Zhang Shuilian;Li Xiaoyuan(Department of Ultrasound,Gaozhou People’s Hospital of Guangdong Province,Gaozhou 525200,China)

机构地区：[1]广东省高州市人民医院超声科,高州525200

出　　处：《现代仪器与医疗》2022年第1期42-44,共3页Modern Instruments & Medical Treatment

基　　金：茂名市科技计划项目,项目名称:E超弹性成像评估肝脏恶性肿瘤患者非肿瘤区域肝质纤维化的临床价值研究,项目编号:2017175。

摘　　要：目的探讨E超弹性成像评估肝癌患者非肿瘤区域肝质纤维化的临床价值.方法选取2017年5月~2018年8月收治的肝癌患者109例为研究组,另选取同期健康体检者49例为对照组.两组均接受E超弹性成像检查,测量非肿瘤区域肝质肝弹性杨氏模量值;统计研究组与对照组、研究组不同肝纤维化情况患者肝弹性杨氏模量值,并分析肝弹性杨氏模量值与肝癌非肿瘤区域肝质纤维化的关联性.结果研究组肝弹性杨氏模量值高于对照组(P<0.05);不同肝纤维化情况者肝弹性杨氏模量值间存在显著差异(P<0.05);Pearson检验可知,肝弹性杨氏模量值与肝癌非肿瘤区域肝质纤维化分期间存在显著正相关关系(P<0.05).结论SWE在肝癌非肿瘤区域肝质纤维化评估中具有较高应用价值,可明确肝纤维化发生情况及其分期,为临床制定相关干预方案提供指导依据.Objective To study the clinical value of E-ultrasound imaging in evaluating hepatic fibrosis in non-tumor areas of patients with liver cancer.Methods A total of 109 liver cancer patients admitted from May 2017 to August 2018 were selected as the study group,and 49 patients with healthy physical examination during the same period were selected as the control group.Both groups underwent E-hyperelasticity imaging to measure the Young’s modulus of liver elasticity in the non-tumor area;the Young’s modulus of liver elasticity of the study group and the control group and the study group with different liver fibrosis conditions were counted,and the liver was analyzed.The relationship between Young’s modulus of elasticity and hepatic fibrosis in non-tumor areas of liver cancer.Results The Young’s modulus of liver elasticity in the study group was higher than that in the control group(P<0.05).There are significant differences in the Young’s modulus of liver elasticity in patients with different liver fibrosis(P<0.05).Pearson test shows that there is a significant positive correlation between the Young’s modulus of liver elasticity and the period of hepatic fibrosis in non-tumor areas of liver cancer(P<0.05).Conclusion SWE has high application value in the evaluation of liver fibrosis in non-tumor areas of liver cancer.It can clarify the occurrence and staging of liver fibrosis,and provide guidance for clinical development of relevant intervention programs.

关 键 词：E超弹性成像 肝癌 非肿瘤区域 肝质纤维化 

分 类 号：R197.39[医药卫生—卫生事业管理]