备孕期、妊娠期和哺乳期过敏原免疫治疗的研究进展  

Progress on allergen immunotherapy during pre-pregnancy,pregnancy,and lactation periods

作　　者：贺宁 马婷婷 唐宁波 王洪田 Ning He;Tingting Ma;Ningbo Tang;Hongtian Wang(Department of Allergy,Yantai Yuhuangding Hospital of Qingdao University,Yantai 264000,China;Department of Allergy,Beijing Shijitan Hospital,Capital Medical University,Beijing 100038,China)

机构地区：[1]青岛大学附属烟台毓璜顶医院变态反应科,烟台264000 [2]首都医科大学附属北京世纪坛医院变态反应科,北京100038

出　　处：《中华围产医学杂志》2022年第4期307-312,共6页Chinese Journal of Perinatal Medicine

基　　金：国家自然科学基金(81670901, 81371074);北京市教委与北京市自然科学基金委联合重点项目(KZ202110025030)。

摘　　要：过敏原免疫治疗(allergen immunotherapy,AIT),又称过敏原疫苗脱敏治疗,是唯一能够改变过敏性疾病自然进程的治疗方法。妊娠期女性AIT是新生儿过敏的保护因素。现有证据显示,不推荐在备孕期、妊娠期、哺乳期开始AIT;AIT期间意外妊娠,无需终止妊娠;AIT对胎儿和婴幼儿无明显不良影响;备孕期、妊娠期、哺乳期可继续维持量AIT。Allergen immunotherapy(AIT),also known as allergen vaccine desensitization,is currently the only treatment that can change the natural course of allergic diseases.AIT for pregnant women is a protective factor for neonatal allergies.Existing findings suggest that AIT should not be started during pre-pregnancy,pregnancy,or lactation periods,but can be continued if has already been started before;unexpected pregnancy during AIT does not require termination;AIT shows no obvious adverse effects on fetuses,infants,and young children.The latest evidence on the effectiveness and safety of AIT during pre-pregnancy,pregnancy,and lactation periods were reviewed.

关 键 词：超敏反应 脱敏法 免疫 妊娠 母乳喂养 治疗结果 

分 类 号：R593.1[医药卫生—内科学]