针刺联合高压氧、红外线照射治疗糖尿病周围神经病变临床研究  

Clinical Study on Acupuncture Combined with Hyperbaric Oxygen and Infrared Radiation for Diabetic Peripheral Neuropathy

作　　者：王杰 马炳全[1] 郭红丽[1] WANG Jie;MA Bingquan;GUO Hongli

机构地区：[1]郑州大学第一附属医院康复医学科,河南郑州450052

出　　处：《新中医》2022年第6期169-172,共4页New Chinese Medicine

摘　　要：目的:观察针刺联合高压氧、红外线照射治疗糖尿病周围神经病变(DPN)的临床疗效。方法:选取96例DPN患者,按随机数字表法分为对照组和观察组,每组48例。对照组采用高压氧、红外线照射治疗,观察组采用针刺联合高压氧、红外线照射治疗,2组均治疗3周。比较2组临床疗效;比较2组治疗前后神经传导速度,血清炎症因子、血浆同型半胱氨酸(Hcy)水平。结果:观察组总有效率93.75%,高于对照组79.17%(P<0.05)。治疗后,2组正中神经感觉神经、运动神经传导速度,腓总神经感觉神经、运动神经传导速度均较治疗前增大(P<0.05),观察组正中神经感觉神经、运动神经传导速度,腓总神经感觉神经、运动神经传导速度均大于对照组(P<0.05)。治疗后,2组血清白细胞介素(IL)-1β、IL-6、肿瘤坏死因子-α (TNF-α)及血浆Hcy水平均较治疗前降低(P<0.05),观察组血清IL-1β、IL-6、TNF-α及血浆Hcy水平均低于对照组(P<0.05)。结论:针刺联合高压氧、红外线照射治疗DPN临床疗效较好,可提高患者的感觉神经和运动神经传导速度,降低血清炎症因子及血浆Hcy水平。Objective: To observe the clinical effect of acupuncture combined with hyperbaric oxygen and infrared radiation for diabetic peripheral neuropathy(DPN). Methods:A total of 96 cases of DPN patients were selected and divided into the control group and the observation group according to the random number table method,with 48 cases in each group.The control group was treated with hyperbaric oxygen and infrared radiation, and the observation group was treated with acupuncture combined with hyperbaric oxygen and infrared radiation. Both groups were treated for three weeks. The clinical effects in the two groups were compared. Before and after treatment,the nerve conduction velocity and the levels of serum inflammatory factors and plasma homocysteine(Hcy) in the two groups were compared. Results:The total effective rate was 93.75% in the observation group,higher than that of 79.17% in the control group(P<0.05). After treatment,the conduction velocity of sensory nerve and motor nerve in median nerve and common peroneal nerve in the two groups was increased when compared with that before treatment(P<0.05), and the above conduction velocities in the observation group were faster than those in the control group(P<0.05). After treatment,the levels of interleukin(IL)-1β,IL-6 and tumor necrosis factor-α(TNF-α) in serum and plasma Hcy in the two groups were decreased when compared with those before treatment(P<0.05),and the above levels in the observation group were lower than those in the control group(P<0.05). Conclusion:The therapy of acupuncture combined with hyperbaric oxygen and infrared radiation has a good clinical effect in treating DPN,which can improve the conduction velocity of sensory and motor nerves,and reduce the levels of serum inflammatory factors and plasma Hcy.

关 键 词：糖尿病周围神经病变 针刺 高压氧 红外线照射 神经传导速度 炎症因子 同型半胱氨酸 

分 类 号：R587.2[医药卫生—内分泌]