刍议清络法论治特发性肺纤维化急性发作  

2Discussion On the Treatment of Acute Attack of Idiopathic Pulmonary Fibrosis with The Method of Clearing Collaterals

作　　者：于睿智 吕晓东[1] 庞立健[2] 王天娇 杨丽[2] Yu Ruizhi;Lyu Xiaodong;Pang Lijian;Wang Tianjiao;Yang Li(School of Graduates,Liaoning University of Traditional Chinese Medicine,Shenyang 1100032,China;The Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,Shenyang 110032,China)

机构地区：[1]辽宁中医药大学研究生院,沈阳1100032 [2]辽宁中医药大学附属医院,沈阳110032

出　　处：《世界科学技术-中医药现代化》2021年第11期4305-4309,共5页Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology

基　　金：辽宁省委辽宁省“兴辽英才计划”项目高水平创新团队(XLYC1808011):肺络病证治体系构建及应用,负责人:吕晓东;辽宁省科技厅辽宁省科学技术计划项目(2019JH2/10300023):益气养阴活血通络法协调LncRNA-miRNA-mRNA网络调控TGF-β1/Smads信号通路干预特发性肺纤维化的机制研究,负责人:吕晓东;沈阳市中青年科技人才支持计划项目(RC200156):基于TGF-β1/Smads信号传导通路的清络饮干预特发性肺纤维化急性加重细胞凋亡机制研究,负责人:庞立健。

摘　　要：本文通过对特发性肺纤维化急性发作病因病机的分析,认为其病因为外邪或内伤引动肺络虚火,从阳化热,病机为“肺热”“、络瘀”;并结合其病因病机,探究归纳《温病条辨》中清络法和中药复方清络饮在论治特发性肺纤维化急性发作时的理论基础,为临床中论治特发性肺纤维化急性发作,改善患者症状提供新方法,为肺络病证治体系构建及应用提供新思路。Through the analysis of the etiology and pathogenesis of idiopathic pulmonary fibrosis(IPF), the author thinks that the etiology of IPF is deficient fire in lung collaterals and transforming heat from yang due to external pathogen or internal injury, and the pathogenesis is“lung heat”and“collateral stasis”. Combined with its etiology and pathogenesis,this paper explored and summarized the theoretical basis for the treatment of acute episode of idiopathic pulmonary fibrosis in Detailed Analysis of Epidemic Warm Diseases and Chinese medicine compound Qingluo Decoction, so as to provide a new method for the treatment of acute episode of idiopathic pulmonary fibrosis, improve the symptoms of patients, and provide new ideas for the construction and application of lung collateral disease syndrome treatment system.

关 键 词：特发性肺纤维化急性发作 肺痿 络病 清络法 清络饮 

分 类 号：R259[医药卫生—中西医结合]