针灸网络生物学  

Network biology in acupuncture

作　　者：陈勇 李柠岑 陈波[1,2,3] 郭义 陈泽林[1,2,3] 公一囡 单凯[1,2] 王美娟 CHEN Yong;LI Ning-cen;CHEN Bo;GUO Yi;CHEN Ze-lin;GONG Yi-nan;SHAN Kai;WANG Mei-juan(Research Center of Experimental Acupuncture Science,Tianjin Un iversity of Traditional Chinese Medicine,Tianjin 301617,China;School of Acupuncture-Moxibustion and Tuina,Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China;National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion,Tianjin 301617,China;School of Traditional Chinese Medicine,Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China)

机构地区：[1]天津中医药大学实验针灸学研究中心,天津301617 [2]天津中医药大学针灸推拿学院,天津301617 [3]国家中医针灸临床医学研究中心,天津301617 [4]天津中医药大学中医学院,天津301617

出　　处：《中华中医药杂志》2021年第11期6288-6293,共6页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家自然科学基金青年科学基金项目(No.82004467);中国科协青年人才托举工程项目(No.2019-2021ZGZJXH-QNRC001);天津市自然科学基金青年项目(No.18JCQNJC82400);天津市教委科研计划项目(No.2017KJ143);天津市卫生健康委员会中医中西医结合科研课题重点项目(No.2019052);天津中医药大学研究生创新项目(No.YJSKC-20191007,No.YJSKC-20191008,No.YJSKC-20191036);天津市研究生科研创新项目(No.2019YJSB139)。

摘　　要：针灸起效作用机制是针灸研究的关键科学问题。目前,基于还原论进行的针灸描述性、验证性研究取得了大量的成果,但这些研究多为线性研究,研究两点之间的因果关系,而对针灸的网络调节作用尚未有清晰的认识和深入的研究。文章从制约针灸临床和基础研究的瓶颈入手,客观分析了导致现有问题的原因,总结了针灸基本特点与网络生物学研究模式的共同之处,提炼总结出针灸网络生物学的概念及基本研究内容,并阐述了从外泌体入手进行针灸网络生物学研究的科学性,希望可以为解决针灸研究中的关键科学问题和提高针灸临床疗效提供创新思路与方法依据。The mechanism of effect of acupuncture is a key scientific problem in acupuncture research. At present,descriptive and confirmatory studies of acupuncture based on reductionism have made a lot of achievements, but most of these studies are linear studies, which study the causal relationship between the two points. However, there is no clear understanding and in-depth research on the network regulation of acupuncture. Starting from the bottleneck restricting the clinical and basic research of acupuncture, this paper objectively analyzes the causes of the existing problems, summarizes the basic characteristics of acupuncture and network biology research model in common, refines and summarizes the concept and basic research content of network biology in acupuncture, and expounds the scientificity of network biology in acupuncture from the perspective of exosomes, hoping to provide innovative ideas and methods for solving the problems in acupuncture research and improving the clinical efficacy of acupuncture.

关 键 词：网络调节 网络生物学 针灸网络生物学 针灸学 

分 类 号：R245[医药卫生—针灸推拿学]