不同剂量阿芬太尼联合丙泊酚对无痛胃镜检查患者的影响  

Effects of Different Doses of Alfentanil Combined with Propofol on Patients with Painless Gastroscopy

作　　者：傅丹泓 FU Danhong(Rehabilitation Hospital Affiliated to Fujian University Traditional Chinese Medicine,Fuzhou 350003,China)

机构地区：[1]福建中医药大学附属康复医院,福建福州350003

出　　处：《中外医学研究》2022年第10期123-126,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:探讨不同剂量阿芬太尼联合丙泊酚对无痛胃镜检查患者的影响。方法:选取福建中医药大学附属康复医院2019年1月-2021年4月收治的90例无痛胃镜检查患者。按随机数字表法分为对照组和观察组,各45例。对照组给予小剂量阿芬太尼联合丙泊酚麻醉,观察组给予大剂量阿芬太尼联合丙泊酚麻醉。比较两组丙泊酚总用量、患者苏醒时间、胃镜操作时间、意识消失时间、镇痛总有效率及不良反应。记录两组入室时(T_(0))、诱导后1 min(T_(1))、5 min(T_(2))、检查结束时(T_(3))的平均动脉压、心率、血氧饱和度。结果:观察组丙泊酚总用量少于对照组,患者苏醒时间、胃镜操作时间、意识消失时间均短于对照组(P<0.05)。观察组镇痛总有效率高于对照组(P<0.05)。两组T;时平均动脉压、心率、血氧饱和度比较差异均无统计学意义(P>0.05),两组T_(1)、T_(2)、T_(3)时平均动脉压、心率、血氧饱和度均较T_(0)时显著下降,观察组T_(1)、T_(2)、T_(3)时血氧饱和度均高于对照组,而心率均低于对照组(P<0.05),两组T_(1)、T_(2)、T_(3)时平均动脉压比较差异无统计学意义(P>0.05)。观察组呛咳发生率低于对照组,呼吸抑制和循环抑制发生率均高于对照组(P<0.05)。结论:对无痛胃镜检查患者使用大剂量阿芬太尼联合丙泊酚麻醉,可有效提高麻醉效果和镇痛效果,维持生命体征稳定。Objective:To investigate the effects of different doses of Alfentanil combined with Propofol on patients with painless gastroscopy.Method:A total of 90 patients with painless gastroscopy admitted to Rehabilitation Hospital Affiliated to Fujian University Traditional Chinese Medicine from January 2019 to April 2021 were selected.They were divided into control group and observation group by random number table method,with 45 cases in each group.The control group was given low dose Alfentanil combined with Propofol anesthesia,and the observation group was given large dose Alfentanil combined with Propofol anesthesia.The total dosage of Propofol,the time of patients’awakening,the operation time of gastroscopy,the time of consciousness disappearance and the total effective rate of analgesia and adverse reactions of the two groups were compared.The mean arterial pressure,heart rate,blood oxygen saturation of the two groups were recorded at the time of entering the room(T_(0)),1 min(T_(1)),5 min(T_(2))after induction and at the end of examination(T_(3)).Result:The total dosage of Propofol in the observation group was less than that in the control group,and the time of patients’awakening,the operation time of gastroscopy,the time of consciousness disappearance in the observation group were shorter than those in the control group(P<0.05).The total effective rate of analgesia in the observation group was higher than that in the control group(P<0.05).There were no significant differences in mean arterial pressure,heart rate and blood oxygen saturation between the two groups at T;(P>0.05).The mean arterial pressure,heart rate and blood oxygen saturation at T_(1),T_(2),T_(3)of the two groups were significantly lower than those at T_(0),the blood oxygen saturation of observation group was higher than that of control group from T_(1),T_(2),T_(3),while the heart rate was lower than that of control group(P<0.05),there was no significant difference in mean arterial pressure at T_(1),T_(2),T_(3)between the two groups(P>0.05).Th

关 键 词：无痛胃镜检查 阿芬太尼 丙泊酚 麻醉效果 不良反应 

分 类 号：R614[医药卫生—麻醉学]