柴胡疏肝散联合生物反馈疗法治疗盆底失弛缓综合征型便秘的效果观察  

The Effect of Chaihu Shugan Powder Combined with Biofeedback Therapy in Treating Constipation of Pelvic Floor Achalasia Syndrome

作　　者：纪亚丽 高永金[2] 邱榕[2] JI Yali;GAO Yongjin;QIU Rong(Zhenjiang Hospital of Integrated Traditional Chinese and Western Medicine,Zhenjiang 212000,China;不详)

机构地区：[1]镇江市中西医结合医院,江苏镇江212000 [2]江苏大学附属医院

出　　处：《中外医学研究》2022年第11期31-35,共5页CHINESE AND FOREIGN MEDICAL RESEARCH

基　　金：镇江市第二批老中医药专家学术经验继承项目(镇卫中医[2018]11号);江苏省中医药局科技项目(YB2017080)。

摘　　要：目的:观察柴胡疏肝散联合生物反馈疗法在盆底失弛缓综合征型便秘治疗中的应用效果。方法:选取2017年1月-2020年12月镇江市中西医结合医院接收的74例盆底失弛缓综合征型便秘患者,根据治疗方法不同分为对照组及观察组,每组37例,对照组予以生物反馈疗法治疗,观察组加用柴胡疏肝散口服治疗,对比其治疗有效率、中医症候积分、肛管直肠压力,以及血清生长抑素(SS)、P物质(SP)和胃动素(MTL)水平。结果:观察组治疗总有效率(91.89%)比对照组(72.97%)高,差异有统计学意义(P<0.05);两组中医症候积分治疗前对比,差异无统计学意义(P>0.05),治疗后观察组较对照组低,差异有统计学意义(P<0.05);肛管直肠压力,力排时肛管残余压、肛管静息压、直肠肛管压差、肛管收缩压方面,两组治疗前差异无统计学意义(P>0.05),治疗后,观察组力排时肛管残余压和直肠肛管压差比对照组优,差异有统计学意义(P<0.05),而肛管收缩压、肛管静息压两组差异无统计学意义(P>0.05);血清SS、SP和MTL水平,两组治疗前对比差异无统计学意义(P>0.05);观察组治疗后较对照组优,差异有统计学意义(P<0.05)。结论:柴胡疏肝散联合生物反馈疗法在盆底失弛缓综合征型便秘治疗中应用效果明显,能明显减轻临床症状,有助于患者提高力排时肛管残余压,改善胃肠激素水平,具有较高的临床应用价值。Objective:To observe the effect of Chaihu Shugan Powder combined with biofeedback therapy in the treatment of constipation of pelvic floor achalasia syndrome.Method:A total of 74 patients with pelvic floor achalasia syndrome type constipation received by Zhenjiang Integrated Traditional Chinese and Western Medicine Hospital from January 2017 to December 2020 were divided into control group and observation group according to different treatment methods,with 37 cases in each group.The control group was treated with biofeedback therapy,and the observation group was treated with Chaihu Shugan Powder.The treatment efficiency,TCM syndrome scores,anorectal pressure,serum somatostatin(SS)and substance P(SP)and motilin(MTL)levels in two groups were compared.Result:The total effective rate of treatment in the observation group(91.89%)was higher than the control group(72.97%),the difference was significant(P<0.05).The TCM syndrome scores in the two groups before treatment had no significant difference(P>0.05),the observation group was lower than the control group after treatment,and the difference was significant(P<0.05).For anorectal pressure,residual pressure in the anal canal,resting pressure in the anal canal,differential pressure in the rectal anal canal,and systolic pressure in the anal canal before treatment in two groups were no significant differences(P>0.05).After treatment,the residual pressure of the anal canal and the pressure difference of the rectum and anal canal in the observation group were better than those of the control group during force discharge,the differences were significant(P>0.05).There were no significant differences in systolic pressure in the anal canal and resting pressure in the anal canal between the two groups(P>0.05);serum SS,SP and MTL levels were not significantly different between the two groups before treatment(P>0.05);the observation group were better than the control group after treatment,with significant differences(P<0.05).Conclusion:Chaihu Shugan Powder combined with biofeedback

关 键 词：柴胡疏肝散 生物反馈疗法 盆底失弛缓综合征型便秘 中医症候积分 肛管直肠压力 胃肠激素水平 

分 类 号：R711.5[医药卫生—妇产科学]