鸡脂肪代谢的分子调控  

Molecular Regulation of Fat Metabolism in Chicken

作　　者：闫世雄 张芯燕 简宗辉 李颜攸 柏毅承 胡梅 豆腾飞 贾俊静[1] YAN Shixiong;ZHANG Xinyan;JIAN Zonghui;LI Yanyou;BAI Yicheng;HU Mei;DOU Tengfei;JIA Junjing(College of Animal Science and Technology,Yunnan Agricultural University,Kunming,Yunnan 650201)

机构地区：[1]云南农业大学动物科学技术学院,云南昆明650201

出　　处：《中国家禽》2022年第4期90-100,共11页China Poultry

基　　金：国家自然科学基金项目(U1702232);云南省科技厅邱声祥院士工作站项目(202005AF150039);云南省教育厅科学研究基金(2021J0107)。

摘　　要：鸡是生物医学研究领域重要的实验动物模型,同时也是畜禽养殖业中重要的经济动物。在家禽养殖业中,鸡脂肪过度沉积会影响饲料效率、生产成本、肉品质和消费者健康,而脂肪代谢是一个复杂的分子调控过程,调控脂肪代谢的具体机制还需进一步研究。文章从转录和转录后水平揭示鸡脂肪代谢过程中关键基因、转录因子、microRNAs(miRNAs)和激素间相互调控机制,为探究鸡脂肪代谢提供新见解,以期鉴定功能性分子标记,促进优良品种选育,减少脂肪过度沉积。Chicken is an important experimental animal model in biomedical research field and an important economic animal in livestock and poultry industry. In poultry industry, excessive fat deposition affects feed efficiency, production cost, meat quality, and consumer′s health. Chicken fat metabolism is a complex molecular regulatory process, the specific mechanism of regulating fat metabolism needs further study. Therefore, this review revealed fat metabolism of key genes, transcription factors, microRNAs(miRNAs) and hormonal regulation mechanism from the transcriptional and post-transcriptional level. This paper would provide new insights into fat metabolism in chickens, identify functional molecular markers to promote breeding of good varieties and reduce excessive fat deposition.

关 键 词：鸡 脂肪代谢 脂肪沉积 分子调控 

分 类 号：S855.9[农业科学—临床兽医学]