鸡胰岛素耐受性及血液葡萄糖稳态调节研究进展  

Research Progress in Insulin Tolerance and Regulation of Blood Glucose Homeostasis in Chickens

作　　者：王子阳 陈文[1] WANG Ziyang;CHEN Wen(College of Animal Science and Technology,Henan Agricultural University,Zhengzhou 450046,China)

机构地区：[1]河南农业大学动物科技学院,郑州450046

出　　处：《动物营养学报》2022年第4期2123-2129,共7页CHINESE JOURNAL OF ANIMAL NUTRITION

基　　金：国家自然科学基金面上项目(32072748)。

摘　　要：鸡具有极强的胰岛素耐受性,空腹血液葡萄糖浓度是大部分哺乳动物的2倍,却无任何有害效应出现。至今关于鸡对长期高血糖和胰岛素的耐受性机制尚未知。本文针对鸡特殊的胰岛素耐受性及胰岛素信号传导通径、葡萄糖转运体(GLUT)等进行综述,以期为解析鸡的糖代谢机制提供参考,也为人类糖尿病预防与治疗提供思路。Chickens have a strong insulin tolerance,and the concentration of fasting blood glucose is twice as high as that of most mammals,but there are no harmful effects.So far,the mechanism of tolerance of chickens to long-term hyperglycemia and insulin is unknown.This paper reviews the special insulin tolerance,insulin signal transduction pathway and glucose transporter(GLUT)in chickens,in order to provide reference for analyzing the mechanism of glucose metabolism in chickens and for the prevention and treatment of human diabetes.

关 键 词：鸡 胰岛素抵抗 胰岛素信号通经 糖代谢 葡萄糖转运体 

分 类 号：S831[农业科学—畜牧学]