癌症化疗患者经济毒性水平及影响因素分析  

Analysis on Level of Financial Toxicity and Its Influencing Factors in Cancer Patients Undergoing Chemotherapy

作　　者：董奥 姜玲[2] 王静[2] 李岩 冉明 张国琴[1] DONG Ao;JIANG Ling;WANG Jing;LI Yan;RAN Ming;ZHANG Guoqin(Shihezi University School of Medicine,Shihezi,Xinjiang 832000;The First Affiliated Hospital of Shihezi University School of Medicine,Shihezi,Xinjiang 832000;Inner Mongolia Medical College,Hohhot,Inner Mongolia 010000)

机构地区：[1]石河子大学医学院,新疆石河子832000 [2]石河子大学医学院第一附属医院,新疆石河子832000 [3]内蒙古医科大学护理学院,内蒙古呼和浩特010000

出　　处：《上海护理》2022年第5期27-31,共5页Shanghai Nursing

基　　金：内蒙古医科大学“科技百万工程”项目[YKD2020KJBW(LH)010]。

摘　　要：目的调查癌症化疗患者经济毒性现状,并分析其影响因素。方法采用便利抽样法,选取2020年11月至2021年6月收治于石河子大学医学院第一附属医院肿瘤内科的288例患者作为研究对象。采用一般资料调查表、中文版经济毒性综合评分量表、社会支持评定量表对其进行调查。结果癌症化疗患者经济毒性总分为(21.72±7.88)分,社会支持评定量表得分为(40.42±6.50)分。单因素分析显示,不同年龄、文化程度、居住地、工作状况、医疗支付方式、家庭人均月收入、肿瘤部位、肿瘤分期、是否转移、是否使用靶向药物的患者经济毒性得分比较,差异有统计学意义(P<0.05)。癌症化疗患者经济毒性得分与社会支持总分和各维度得分均呈正相关(P<0.05)。多元线性回归分析显示,家庭人均月收入、年龄、肿瘤部位、客观支持、是否使用靶向药物、肿瘤分期、文化程度进入回归方程(P<0.05),可解释总变异的49.1%。结论所调查的癌症化疗患者经济毒性评分较高,家庭人均月收入、年龄、肿瘤部位、客观支持、是否使用靶向药物、肿瘤分期、文化程度是癌症化疗患者的经济毒性主要影响因素。医务人员应全程、全面评估癌症化疗患者的经济毒性水平,鼓励患者参与治疗方案成本的讨论,帮助其积极寻求社会支持,以降低患者因治疗相关经济负担产生的痛苦。Objective chemotherapy and analyze the influencing factors.Methods Department of Medical Oncology of the First Affiliated Hospital of Shihezi University School of Medicine from November 2020 to June 2021 were selected as the subjects by convenience sampling.They were investigated using the General Information Questionnaire,the Chinese version of the Comprehensive Score for Financial Toxicity-Functional Assessment of Chronic Illness Therapy(COST-FACIT)and the Social Support Rating Scale(SSRS).ResultsThe total score of financial toxicity was(21.72±7.88)points and the score of SSRS was(40.42±6.50)points for the cancer patients undergoing chemotherapy.Univariate analysis showed that there were significant differences in the financial toxicity scores of patients who were different in age,education level,place of residence,work status,mode of medical payment,household monthly income per person,tumor site,tumor stage,metastasis,and use of targeted drugs(P<0.05).The score of financial toxicity was positively correlated with the total score of social support and the score of each dimension in the cancer patients Pregression analysis showed that household monthlyincome per person,age,tumor site,objectivesupport,use of targeted drugs,tumor stage,andeducation level were entered into the regression equation(P<0.05),explaining 49.1%of the total variation.ConclusionThe cancer patients undergoingchemotherapy investigated have a higher score of financial toxicity.Medical staff should fully assess the levelof financial toxicity in cancer patients undergoing chemotherapy throughout their treatment,encourage them toparticipate in the discussion of the cost of their treatment options and help them seek social support,in order toreduce the pain caused by treatment-related economic burden.

关 键 词：癌症 化疗 经济毒性 社会支持 影响因素 

分 类 号：R473.73[医药卫生—护理学]