浙江省金华市某县2008—2020年手足口病流行特征分析  

Analysis of epidemiological characteristics of hand,foot,and mouth disease in a county of Jinhua City,Zhejiang Province,2008‒2020

作　　者：王平平[1] 周璐 吴红照[1] 徐成涛 吴玉环 陆一涵[2] WANG Pingping;ZHOU Lu;WU Hongzhao;XU Chengtao;WU Yuhuan;LU Yihan(Pujiang Center for Disease Control and Prevention,Jinhua,Zhejiang 321000,China;School of Public Health,Fudan University,Shanghai 200032,China)

机构地区：[1]金华市浦江县疾病预防控制中心,浙江金华321000 [2]复旦大学公共卫生学院,上海200032

出　　处：《上海预防医学》2022年第3期210-213,共4页Shanghai Journal of Preventive Medicine

基　　金：金华市浦江县第二批科学技术研究计划项目(编号:17W13)。

摘　　要：【目的】分析金华市浦江县手足口病流行病学及病原学特征,为制定防控策略提供依据。【方法】采用描述性流行病学方法,对从中国疾病预防控制信息系统中获取的2008—2020年浦江县手足口病病例信息及病原学检测结果进行分析。【结果】2008—2020年浦江县共报告手足口病病例9393例,年均发病率为182.3/10万,呈现大小年交替流行趋势。季节分布呈双峰型,发病主要集中在5—7月与11—12月。城区手足口病发病率明显高于农村地区,发病率与人口密度呈正相关。病例以5岁以下儿童为主,占病例总数的94.9%;男童发病率高于女童;散居儿童和幼托儿童占病例总数的97.3%。2008—2020年浦江县实验室确诊病例558例,重症病例皆为肠道病毒71型(EV71)。【结论】浦江县手足口病的血清型在2008—2020年间不断发生改变,但EV71仍为重症病例的主要血清型,需要加强对手足口病病原学的监测,并继续推动EV71疫苗接种等相关工作。[Objective]To determine the epidemiological and etiological characteristics of hand,foot,and mouth disease(HFMD)in Pujiang County from 2008 through 2020,so as to provide scientific evidence for prevention and control measures.[Methods]Descriptive epidemiological analysis was used to analyze HFMD cases retrieved in the Chinese Information System for Disease Control and Prevention in Pujiang County during 2008‒2020.[Results]From 2008 through 2020,a total of 9393 cases were documented in Pujiang County,with an annual incidence of 182.3 per 100000,showing a trend of alternating high-incidence and low-incidence years.The seasonal distribution was bimodal,and the incidence peaked in May-July and November-December.The incidence of HFMD in urban areas was significantly higher than that in rural areas,and the incidence was positively correlated with population density.Majority of cases(94.9%)were children under 5 years old,of which boys had higher incidence than girls.The number of documented cases was the highest among preschool children living in families and kindergartens,accounting for 97.3%.Totally,558 cases were laboratory confirmed in Pujiang County in 2008-2020,of which severe cases were all caused by EV71 infection.[Conclusion]Enterovirus serotypes in HFMD have continually changed from 2008 through 2020 in Pujiang County.However,severe HFMD remains principally attributable to EV71 infection,suggesting that it is necessary to strengthen the surveillance on the etiology of HFMD.In addition,it warrants further promotion of EV71 vaccination.

关 键 词：手足口病 流行特征 病原学 肠道病毒71型 监测 

分 类 号：R512.5[医药卫生—内科学]