113例呼吸系统疾病患者红细胞血型不规则抗体的回顾研究  

Retrospective analysis of irregular antibodies of blood groups in 113 patients with respiratory diseases

作　　者：陈舒[1] 许先国[1] 洪小珍[1] 朱发明[1] CHEN Shu;XU Xianguo;HONG Xiaozhen(Blood Center of Zhejiang Province,Key Laboratory of Blood Safety Research of Zhejiang Province,Hangzhou 310052,China)

机构地区：[1]浙江省血液中心输血医学研究所,浙江省血液安全研究重点实验室,浙江杭州310052

出　　处：《全科医学临床与教育》2022年第4期318-321,共4页Clinical Education of General Practice

基　　金：浙江省基础公益研究计划(LGF20H080002)。

摘　　要：目的研究呼吸系统疾病患者红细胞血型不规则抗体的特点。方法回顾性分析2012年11月至2021年6月间收集的113例呼吸系统疾病患者红细胞血型不规则抗体鉴定结果。结果本研究呼吸系统疾病患者以肺炎类和肺部肿瘤类多见。113例患者中有86例患者检出15种红细胞血型不规则抗体,占比前三位的分别是抗-M(25.58%)、冷凝集素(25.58%)、抗-E(15.12%)。肺炎和肺部肿瘤患者抗-M比例分别为12.82%和44.44%,差异有统计学意义(χ^(2)=5.32,P<0.05);抗-E比例分别为17.95%和22.22%,差异无统计学意义(χ^(2)=0.00,P>0.05);冷凝集素比例分别为33.33%和5.56%,差异无统计学意义(χ^(2)=3.74,P>0.05)。结论肺部疾病患者红细胞血型不规则抗体以抗-M、冷凝集素和抗-E多见。Objective To study the characteristics of irregular blood groups antibodies in the patients with respiratory diseases.Methods The identification results of irregular antibodies in the patients with respiratory diseases were collected from November 2012 to June 2021 for retrospectively analysis.Results A total of 113 patients were collected.Among them,86 patients were unexpectedly positive for antibodies,which were mostly found in anti-M(25.58%),cold agglutinin(25.58%),and anti-E(15.12%).The anti-M frequency of the patients with pneumonia and lung cancer were 12.82%and 44.44%,respectively.The difference was statistically significant(χ^(2)=5.32,P<0.05).There was no significant difference in the anti-E and cold agglutinin frequencies between the patients with pneumonia and the lung tumor(17.95%vs 22.22%,and 33.33%vs 5.56%)(χ^(2)=0.00,3.74,P>0.05).Conclusion The irregular antibodies of blood groups in the patients with respiratory diseases are mainly anti-M,cold agglutinin and anti-E.

关 键 词：呼吸系统疾病 红细胞血型不规则抗体 

分 类 号：R446.6[医药卫生—诊断学] R56[医药卫生—临床医学]