AB073.Correlations between control of saccadic eye movements and performance in other cognitive tasks in younger adults,older adults and patients with Parkinson’s disease  

作　　者：Julie Ouerfelli-Ethier Basma Elsaeid Julie Des Groseilliers Lydia Ouchene Douglas P.Munoz Gunnar Blohm Aarlenne Z.Khan 

机构地区：[1]École d'Optométrie,Universitéde Montréal,Montréal,QC,Canada [2]Center for Neuroscience Studies,Queen's University,Kingston,ON,Canada [3]Department of Medicine and Health Sciences,Universitéde Sherbrooke,Sherbrooke,QC,Canada

出　　处：《Annals of Eye Science》2018年第1期479-479,共1页眼科学年鉴（英文）

摘　　要：Background:Cognitive control is defined as the ability to act flexibly in the environment by either behaving automatically or inhibiting said automatic behaviour and it can be measured using an interleaved pro/anti-saccade task.Decline in cognitive control has been attributed to normal aging and neurological illnesses such as Parkinson’s disease(PD)as well as decline in other cognitive abilities.This parallel might highlight the role played by cognitive control in information processing and working memory.However,little is known about the relationship between cognitive control and other cognitive processes such as visual memory,decision making,and visual search.We thus propose to correlate the incidence of impaired cognitive control with deficits in visual memory,decision making and visual search in three groups:younger adults,older adults and patients with idiopathic PD.Methods:Seventy-one participants,namely 34 adults(M=22.75,SD=3.8),22 older adults(M=67.4,SD=8.3),and 20 PD patients(M=65.59,SD=8.2)performed four tasks:interleaved pro/anti-saccade,visual memory,decision making,and serial and pop-out visual search.Results:Results show that within each group,anti-saccade error rate(ER)were significantly and negatively correlated with visual memory ER(ryounger=−0.378,P=0.036;rolder=−0.440,Polder=0.046;rPD=−0.609,P=0.016).On the other hand,correct decision-making reaction times(RT)were significantly correlated with anti-saccade ER,and RTs only in older adults(rER=0.529,P=0.014;rRT=0.512,P=0.018)and PD patients(rER=0.727,P=0.012;rRT=0.769,P=0.001).For visual search,PD patients showed a significant relationship between RTs for correct pro-saccades and pop-out(r=0.665,P=0.007),and serial(r=0.641,P=0.010)search RTs.Furthermore,there was a significant correlation between MoCA scores and anti-saccade RTs(r=−0.559,P=0.030)and ER(r=−0.562,P=0.029)in PD patients.Taken together,these results support the hypothesis of PD patients’reliance on bottom-up processes as top-down processes decline.For younger adults,the

关 键 词：SACCADE cognitive control Parkinson's disease 

分 类 号：TP3[自动化与计算机技术—计算机科学与技术]