域发联合纳米微晶与点阵CO_(2)激光治疗雄激素性脱发疗效比较研究  

Comparative Study on the Efficacy of Topical Hair Therapy Combined with Nanocrystals and Dot Matrix CO_(2) Laser in the Treatment of Androgenetic Alopecia

作　　者：黄蕾 朱森 李阳 HUANG Lei;ZHU Sen;LI Yang(Department of Medical Cosmetology,Xianyang Hospital,Yan'an University,Xianyang 712000,Shaanxi,China)

机构地区：[1]延安大学咸阳医院医疗美容科,陕西咸阳712000

出　　处：《中国美容医学》2022年第4期9-12,共4页Chinese Journal of Aesthetic Medicine

基　　金：咸阳市科技局课题(编号:2019K02-106)。

摘　　要：目的:观察域发联合纳米微晶与联合点阵CO_(2)激光治疗雄激素性脱发的临床疗效。方法:40例雄激素性脱发男性患者,随机分为点阵组和纳晶组。分别给予域发联合点阵CO_(2)激光治疗和域发联合纳晶治疗,两组均连续治疗6个月,间隔时间1周,治疗后同时使用域发头皮营养液,3次/天,疗程结束后比较两组疗效。结果:两组患者治疗前每平方厘米头发密度与直径比较差异均无统计学意义(P>0.05),而治疗后两组患者每平方厘米头发密度较治疗前明显增多,且点阵组密度数据高于纳晶组(P<0.05);治疗后两组患者每平方厘米头发直径较治疗前明显增加,但点阵组直径与纳晶组直径相比无统计学意义(P>0.05);两组患者治疗前主观评分比较差异无统计学意义(P>0.05),治疗后两组患者主观评分较治疗前明显下降,差异具有统计学意义(P<0.05),且点阵组主观评分低于纳晶组(P<0.05),点阵组总有效率为80%,纳晶组总有效率为70%,差异无统计学意义(P>0.05)。结论:点阵CO_(2)激光和纳米微晶均能够更明显地增加雄激素脱发患者脱发区的毛发密度,其中点阵激光疗效更佳,值得临床推广。Objective To observe the clinical effect of Yufa combined with nano-microneedel and Yufa combined with CO_(2)fractional laser in the treatment of androgenetic alopecia. Methods 40 cases of male patients with androgenetic alopecia were randomly divided into the fractional laser group and the nano-microneedel group, which were treated with Yufa combined with CO_(2)fractional laser therapy and Yufa combined with nanometer therapy, respectively. The treatment lasted for 6months,the interval was 1 week, at the same time usingYufa three times a day after the treament.The clinical effects of different treatments were compared. Results Before treatment, there was no significant difference in hair density and diameter per 1 square centimeter between the two groups(P>0.05),but after the treatment, the hair density per 1 square centimeter in the two groups was significantly increased, and the density data of fractional laser group was higher than that of nano-microneedel group(P<0.05).The hair diameter per 1 square centimeter in the two groups was significantly increased compared with that before treatment, but there was no statistical significance between the two groups(P>0.05).There was no significant difference in the subjective scores between the two groups before treatment(P>0.05), but after treatment the subjective scores of the two groups decreased significantly compared with before(P<0.05), and the subjective scores of the fractional laser group were lower than that of the nano-microneedel group(P<0.05). The total effective rate of the fractional laser group was 80%, and the total effective rate of thenano-microneede group was 70%. Conclusion Both CO_(2)fractional laser and nano-microneede can significantly increase hair density in the hair loss area of patients with androgenetic alopecia, among which fractional laser has better efficacy and is worthy of clinical promotion.

关 键 词：域发 纳米微晶 点阵CO_(2)激光 雄激素性脱发 

分 类 号：R758.71[医药卫生—皮肤病学与性病学]