氨基酮戊酸光动力联合中药面膜治疗玫瑰痤疮疗效分析  

Clinical Effect of Amino-keto-valeric Acid Photodynamic Combined with Traditional Chinese Medicine Facial Mask on Rosary Acne

作　　者：辜东成 冯菊蕊 程茂杰[2] GU Dongcheng;FENG Jurui;CHENG Maojie(Department of Dermatology,Qionghai People's Hospital,Qionghai 571400,Hainan,China;Department of Dermatology,Chongqing of Hospital Traditional Chinese Medicine,Chongqing 400010,China)

机构地区：[1]琼海市人民医院皮肤科,海南琼海571400 [2]重庆市中医院&重庆市第一人民医院皮肤科,重庆400010

出　　处：《中国美容医学》2022年第4期35-38,共4页Chinese Journal of Aesthetic Medicine

摘　　要：目的:探讨氨基酮戊酸光动力联合中药面膜治疗玫瑰痤疮的临床疗效。方法:选取2018年6月-2020年6月笔者医院收治的124例玫瑰痤疮患者为研究对象,采用随机数字表法分为对照组(62例)和研究组(62例),对照组采用氨基酮戊酸光动力治疗,研究组在对照组的基础上给予中药面膜治疗,两组均持续治疗3个月后观察效果。对比两组治疗前后临床症状评分及疗效,统计两组治疗前后皮肤生理指标情况、安全性及停药后1个月、6个月的复发情况。结果:治疗前两组临床症状总评分对比,差异均无统计学意义(P>0.05),治疗后两组临床症状总评分相较治疗前均降低,且研究组治疗后临床症状总评分低于对照组,差异均有统计学意义(P<0.05);研究组总有效率高于对照组(P<0.05)。治疗前两组角质层含水量、皮肤油脂水平对比差异均无统计学意义(P>0.05),治疗后两组角质层含水量、皮肤油脂水平相较于治疗前均提高,差异有统计学意义(P<0.05),治疗后研究组角质层含水量、皮肤油脂水平均高于对照组,差异有统计学意义(P<0.05)。两组总不良反应发生率对比差异无统计学意义(P>0.05)。研究组停药后1个月、6个月复发率(11.29%、24.19%)低于对照组(25.81%、43.55%),差异有统计学意义(P<0.05)。结论:采用氨基酮戊酸光动力联合中药面膜治疗玫瑰痤疮疗效确切,并可有效改善患者临床症状,提高皮肤生理功能,减小复发风险,且安全性良好。Objective To investigate the clinical effect of Amino-keto-valeric acid photodynamic combined with traditional Chinese medicine facial mask on rosary acne. Methods 124 rosacea patients admitted to our hospital were selected as the research objects from June 2018 to June 2020. They were divided into control group(62 cases) and study group(62 cases) using random number table method. The control group was treated with aminolevulinic acid photodynamic therapy, and the study group was treated with a traditional Chinese medicine mask on the basis of the control group. The effects of both groups were observed after continuous treatment for 3 months. The clinical symptom scores and curative effects of the two groups before and after treatment were compared, and the blood and skin physiological indicators of the two groups before and after treatment,safety, and recurrence at 1 month and 6 months after drug withdrawal were counted. Results There was no significant difference in the total scores of clinical symptoms between the two groups before treatment(P>0.05). The total scores of clinical symptoms after treatment in the two groups were lower than before treatment, the difference was statistically significant(P<0.05). The total score of clinical symptoms after treatment in the study group was lower than control group, the difference was statistically significant(P<0.05). The total effective rate of the study group was higher than control group(P<0.05). There was no statistically significant difference in water content of the stratum corneum and skin oil levels between the two groups before treatment(P>0.05). After treatment, the water content of the stratum corneum and skin oil levels of the two groups increased compared with those before treatment, and the difference was statistically significant(P<0.05). The water content of the stratum corneum and skin oil level in the study group were higher than control group after treatment, the difference was statistically significant(P<0.05). There was no significant difference i

关 键 词：氨基酮戊酸光动力疗法 中药面膜 玫瑰痤疮 疗效 

分 类 号：R758.734[医药卫生—皮肤病学与性病学]