Late ischemic stroke and brachiocephalic thrombus in a 65-year-old patient six months after COVID-19 infection:A case report  

作　　者：Kristen Jane Kilby Catherine Anderson-Quiñones Keith Richard Pierce Kirollos Gabrah Ankur Seth Allison Brunson 

机构地区：[1]Department of Pharmacy,Baptist Memorial Hospital-Memphis,Memphis,TN 38120,United States [2]College of Medicine,University of Tennessee Health Science Center,Memphis,TN 38163,United States [3]College of Osteopathic Medicine,New York Institute of Technology,Jonesboro,AR 72401,United States

出　　处：《World Journal of Hematology》2022年第2期13-19,共7页世界血液学杂志

摘　　要：BACKGROUND Although it is well established that coronavirus disease 2019(COVID-19)is associated with inflammation and a prothrombotic state leading to stroke and venous thromboembolism(VTE),the nuances of this association are yet to be uncovered[1].Many studies link elevations in inflammatory markers to cases of thromboembolism.Most reports of thromboembolism associated with COVID-19 occur in the venous circulation during or just after the initial hospitalization due to COVID-19[2].It is unclear how long the hypercoagulable effect of COVID-19 lasts.CASE SUMMARY We present a unique case of a 65-year-old-female who presented to her primary care doctor with a sore throat,cough,fatigue,congestion,diarrhea,headache,and anosmia.She tested positive for severe acute respiratory syndrome coronavirus 2 and received a bamlanivimab infusion 9 days later.After recovering from the acute illness,she received the Pfizer-BioNTech COVID-19 vaccine.Months later,she presented to the Emergency Department(ED)complaining of right sided shoulder pain and motor weakness in her left hand while trying to type on a keyboard.On presentation to the ED,her calculated Padua prediction score for risk of VTE was two and inflammatory markers were not elevated.She was found to have a brachiocephalic artery occlusion as well as an ischemic stroke which was treated with heparin.CONCLUSION This case suggests hypercoagulability due to COVID-19 may extend further than current literature suggests,to at least six months.

关 键 词：COVID-19 Stroke SARS-CoV-2 THROMBUS VACCINE Case report 

分 类 号：R74[医药卫生—神经病学与精神病学]