大动物氦氧模拟潜水舱内微环境的控制  

Control of microenvironments inside a simulated heliox diving chamber for large animals

作　　者：周英杰 张坤 衣洪杰 朱包良 庆龙 徐伟刚 ZHOU Ying-Jie;ZHANG Kun;YI Hong-jie;ZHU Bao-liang;QING Long;XU Wei-gang(Department of Diving and Hyperbaric Medicine,Naval Special Medical Center,Naval Medical University,Shanghai 200433,China;Department of Hyperbaric Oxygen Therapy,the First Affiliated Hospital,Naval Medical University,Shanghai 200433,China;Department of Naval Diving Medicine,Naval Special Medical Center,Naval Medical University,Shanghai 200052,China)

机构地区：[1]海军军医大学海军特色医学中心潜水和高气压医学研究室,上海200433 [2]海军军医大学第一附属医院高压氧治疗科,上海200433 [3]海军军医大学海军特色医学中心海潜科,上海200052

出　　处：《军事医学》2022年第1期34-36,共3页Military Medical Sciences

基　　金：军队后勤科研重点项目(2020A0101);国家“双一流”学科建设项目。

摘　　要：目的 研究建立大动物氦氧潜水实验中加压舱内气体环境的控制方法。方法 遵照模拟潜水基本要求,采用自动操控系统控制压力,使用特定氧浓度的混合气和小量补氧维持氧分压,吸收剂主动吸附清除二氧化碳,舱内空调维持温度,雾化或补水维持湿度。同时采用套舱减少氦氧混合气用量并提高环境控制的精准度。结果 自动操控系统可根据设定的高气压暴露方案精准实现加压、稳压和减压过程,氧分压、二氧化碳分压、温湿度均能有效控制在目标范围。结论 该研究建立的方法符合大动物氦氧模拟潜水实验要求。Objective To establish a method for control of the gas environment in a hyperbaric chamber for large animals in simulated heliox diving experiments. Methods As required by simulated diving,an automatic control system was adopted to control the pressure. A mixture of gases at specified oxygen concentrations and a small amount of oxygen replenishment were used to maintain the partial pressure of oxygen. Active absorbance was adopted to remove carbon dioxide,the cabin air conditioning was used to maintain the temperature,and atomization or water replenishment was used to maintain the humidity. At the same time, "a chamber inside a chamber" was adopted to reduce the consumption of heliox and improve the accuracy of environmental control. Results The automatic control system could accurately accomplish pressurization,stabilization and decompression according to the set exposure profile.The partial pressure of oxygen,partial pressure of carbon dioxide,temperature and humidity could be effectively controlled within the target range.Conclusion The method established in this study conforms to the requirements of heliox simulation diving experiments for large animals.

关 键 词：动物实验 潜水医学 模拟潜水 氦氧潜水 环境控制 

分 类 号：R84[医药卫生—航空、航天与航海医学]