儿童及成人噬血细胞综合征的临床特点  

Clinical features of hemophagocytic syndrome in children and adults

作　　者：孙洪坤[1] 王丽君[2] 于文征[1] 刘晓丹[1] 宋斌[2] SUN Hongkun;WANG Lijun;YU Wenzheng;LIU Xiaodan;SONG Bin(Department of Hematology,Binzhou Medical University Hospital,Binzhou 256603,Shandong,P.R.China;Department of Ophthalmology,Binzhou Medical University Hospital,Binzhou 256603,Shandong,P.R.China)

机构地区：[1]滨州医学院附属医院血液内科,山东滨州256603 [2]滨州医学院附属医院眼科,山东滨州256603

出　　处：《滨州医学院学报》2022年第2期124-126,共3页Journal of Binzhou Medical University

基　　金：滨州医学院科研计划(BY2020KJ20)。

摘　　要：目的 探讨成人及儿童噬血细胞综合征(HPS)患者的临床特点、实验室检查是否存在差异,并协助判断预后、指导治疗。方法 收集初次诊断为HPS的患者资料,分析其相关指标的差别。结果 成人患者与儿童患者比较,在白细胞、血清乳酸脱氢酶、甘油三酯、纤维蛋白原及血清肌酐水平方面存在差异,P均<0.05。结论 在成人与儿童HPS患者中,上述指标的差异提示二者在疾病进展及预后方面不同。objective To investigate the clinical characteristics and laboratory examination of hemophagocytic syndrome(HPS)in adults and children,and to help estimate the prognosis and guide the treatment.Methods The data of patients who were first diagnosed with HPS were collected to analyze the differences in related indicators.Results There were differences in levels of white blood cells,serum lactate dehydrogenase,triglyceride,fibrinogen and serum creatinine between children and adult patients,average P<0.05.Conclusion In adults and children with HPS,the differences of the above indicators suggest that the two may be different in disease progression and prognosis.

关 键 词：儿童 成人 噬血细胞综合征 回顾性 

分 类 号：R552[医药卫生—血液循环系统疾病]