脱氢枞酸结构改性的研究进展  

Research Progress on Structural Modification of Dehydroabietic Acid

作　　者：姜巧娟 赵雅雯 刘从军 JIANG Qiaojuan;ZHAO Yawen;LIU Congjun(School of Chemical Engineering&Food Science,Zhengzhou University of Technology,Zhengzhou,Henan 450044,China)

机构地区：[1]郑州工程技术学院化工食品学院,河南郑州450044

出　　处：《中州大学学报》2022年第2期119-124,共6页Journal of Zhongzhou University

摘　　要：脱氢枞酸是由歧化松香分离得到的一种具有三环二萜骨架结构的天然树脂酸,因其具有广泛的生物活性而备受关注,尤其对其羧基、异丙基等活性部位的结构修饰成为研究热点,以期获得高活性的先导化合物。综述了近年来脱氢枞酸的结构改性,脱氢枞酸的羧基、B环、异丙基的结构修饰以及改造后的衍生物具有较好的乳化、抗菌,荧光、耐腐蚀等性能,对脱氢枞酸改性的未来发展进行展望,为脱氢枞酸改性的相关研究提供参考。Dehydroabietic acid is a natural tricyclic diterpenoid product from disproportionate drosin.It has attracted much attention because of its wide range of biological activities.Especially,to obtain highly active lead compounds by modification of carboxyl and isopropyl groups is becoming a hot spot in all over the world.In this paper,recent developments in structural modification on carboxyl,B ring and isopropyl groups are reviewed with performance improvement,i.e.emulsification,antibacterial,fluorescence,corrosion resistance.Meanwhile,the future development of dehydroabietic acid is further forecasted.It is hopeful for helping the relevant modified studies of dehydroabietic acid.

关 键 词：脱氢枞酸 羧基 苯环 异丙基 改性 

分 类 号：TQ351.471[化学工程]