机构地区:[1]新疆医科大学公共卫生学院,新疆乌鲁木齐830000 [2]新疆医科大学,新疆乌鲁木齐830000
出 处:《预防医学》2022年第5期519-524,共6页CHINA PREVENTIVE MEDICINE JOURNAL
基 金:国家自然科学基金项目(81960608)。
摘 要:目的了解新疆和田地区墨玉县居民代谢性疾病患病情况,为制定代谢性疾病防控策略提供依据。方法通过医院体检病历系统收集2020年墨玉县≥18岁居民的人口学信息、实验室检测和肝胆B超检测资料,分析墨玉县居民肥胖、高血压、糖尿病、血脂异常和脂肪肝等代谢性疾病患病情况。采用多分类logistic回归模型分析代谢性疾病的影响因素。结果调查281803人,其中男性129549人,占49.97%;女性152254人,占54.03%。年龄M(QR)为37.00(22.00)岁。患代谢性疾病134306例,患病率为47.66%;其中,肥胖、高血压、血脂异常、脂肪肝和糖尿病的患病率分别为25.72%、24.77%、12.30%、12.05%和5.49%,均随年龄增长呈上升趋势(χ^(2)_(趋势)=11243.73、14086.41、2109.70、6631.22、2011.15,均P<0.001)。患1种代谢性疾病73811例,占26.19%;患多种代谢性疾病60495例,占21.47%。多分类logistic回归分析结果显示,性别(OR=0.870;0.796)、年龄(OR:1.703~8.701;2.952~18.846)、婚姻状况(OR:1.397~1.845;1.460~2.377)、文化程度(OR:0.891~0.937;0.920~0.924)、职业(OR:1.177~1.270;1.114~2.099)、家族史(OR=1.136;1.390)、饮酒频率(OR:2.038;1.395~2.574)和中心性肥胖(OR=3.448;14.352)与患1种和多种代谢性疾病有统计学关联。结论墨玉县居民代谢性疾病患病率较高。男性、中老年人、文化程度低和不健康生活方式可能增加代谢性疾病的患病风险。Objective To investigate the prevalence of metabolic diseases among residents in Moyu County,Hotan Pre⁃fecture,Xinjiang Uygur Autonomous Region,so as to provide the evidence for developing the control strategy for meta⁃bolic diseases.Methods The demographic features,laboratory examinations and B-mode ultrasonographic examinations of the liver and gall bladder were collected from residents at ages of 18 years and older in Moyu County through the hospital-based medical records system.The prevalence of metabolic diseases was estimated,including obesity,hyperten⁃sion,diabetes,dyslipidemia and fatty liver,and the factors affecting the development of metabolic diseases were identi⁃fied using a multinomial logistic regression model.Results Totally 281803 residents were included in the study,in⁃cluding 129549 men(49.97%)and 152254 women(54.03%)and with a median age of 37.00 years(interquartile range,22.00 years).The overall prevalence of metabolic diseases was 47.66%,and the prevalence rates of obesity,hy⁃pertension,dyslipidemia,fatty liver and diabetes were 25.72%,24.77%,12.30%,12.05%and 5.49%,respectively,which appeared a tendency towards a rise with age(χ^(2)_(trend)=11243.73,14086.41,2109.70,6631.22,and 2011.15,all P<0.001).There were 73811 residents suffering from one metabolic disease(26.19%),and 60495 residents with two and more metabolic diseases(21.47%).Multinomial logistic regression analysis showed that gender(OR=0.870;0.796),age(OR:1.703-8.701;2.952-18.846),marital status(OR:1.397-1.845;1.460-2.377)educational level(OR:0.891-0.937;0.920-0.924),occupation(OR:1.177-1.270;1.114-2.099),family history(OR=1.136;1.390),drinking frequency(OR:2.038;1.395-2.574)and central obesity(OR=3.448;14.352)were factors affecting the development of one or more met⁃abolic diseases.Conclusion The prevalence of metabolic diseases is high among residents in Moyu County.Men,the el⁃derly,a low education level and unhealthy lifestyles may increase the risk of metabolic diseases.
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