肥厚型心肌病患者二尖瓣病变的研究进展  

Research Progress of Mitral Valve Abnormalities in Hypertrophic Cardiomyopathy

作　　者：黄曼芸 黄晓红[1] HUANG Man-yun;HUANG Xiao-hong(Special Medical Treatment Center,National Key Laboratory of Cardiovascular Diseases,Fuwai Hospital,National Center for Cardiovascular Diseases,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100037,China)

机构地区：[1]中国医学科学院北京协和医学院国家心血管病中心阜外医院心血管疾病国家重点实验室特需医疗中心,北京市100037

出　　处：《中国分子心脏病学杂志》2022年第1期4501-4505,共5页Molecular Cardiology of China

基　　金：国家重点研发计划(2016YFC1300901)。

摘　　要：肥厚型心肌病是临床上发病率最高的遗传性心肌病。肥厚型心肌病的二尖瓣病变主要是左心室血流动力学改变与瓣膜的原发异常共同作用的结果。目前二尖瓣病变的具体机制仍不清晰,所以临床上手术方式的选择也各不相同。本文主要对肥厚型心肌病合并二尖瓣病变的机制及临床管理进行综述。Hypertrophic cardiomyopathy(HCM) is the most common hereditary cardiomyopathy clinically.The mitral valve abnormalities in HCM are the result of both the left ventricular hemodynamic change and the primary valve abnormality.However,since the specific mechanism of mitral valve abnormalities is still unclear,the choice of clinical surgical methods stays different.This article mainly reviews the mechanism and clinical management of HCM with mitral valve abnormalities.

关 键 词：肥厚型心肌病 收缩期二尖瓣前移 二尖瓣成形术 二尖瓣置换术 MITRACLIP 

分 类 号：R542.2[医药卫生—心血管疾病] R542.51[医药卫生—内科学]