Pixel 2940nm铒激光联合维生素B12治疗痤疮凹陷性瘢痕的效果  

Efficacy of Pixel 2940nm erbium laser combined with VB12 in treatment of acne pitting scar

作　　者：葛玉珍[1] 李永立[1] 肖洪波 Ge Yuzhen;Li Yongli;Xiao Hongbo(Department of Plastic Surgery,Jiaozuo Municipal Second People's Hospital,Jiaozuo 454000,China)

机构地区：[1]河南省焦作市第二人民医院烧伤整形外科,焦作454000

出　　处：《中华医学美学美容杂志》2022年第2期140-143,共4页Chinese Journal of Medical Aesthetics and Cosmetology

基　　金：河南省科技发展计划(142102310420)。

摘　　要：目的探讨Pixel 2940 nm铒激光联合维生素B12治疗痤疮凹陷性瘢痕的疗效。方法2017年7月至2019年6月,河南省焦作市第二人民医院烧伤整形外科收治痤疮凹陷性瘢痕患者96例,根据随机数字表法分为两组各48例。对照组用常规磨削方法治疗,观察组用Pixel 2940 nm铒激光联合维生素B12治疗,比较两组治疗效果、痤疮瘢痕权重评分(ECCA)、皮肤VISIA检测、不良反应。结果对照组治疗有效37例(77.08%),低于观察组44例(91.67%),两组比较差异有统计学意义(P<0.05)。对照组ECCA评分不良反应发生率为18.75%(9/48),毛孔和紫质两项指标分别为(32.25±8.41)分、(18.24±5.12)分,均高于观察组4.17%(2/48)、(28.24±7.52)分、(15.63±4.34)分;两组比较差异均有统计学意义(均P<0.05)。结论Pixel 2940 nm铒激光联合维生素B12治疗痤疮凹陷性瘢痕的疗效显著,不良反应少、安全性高、值得临床应用。Objective To investigate the efficacy of pixel 2940 nm erbium laser combined with vitamin B12 in the treatment of acne sunken scar.Methods From July 2017 to June 2019,96 patients with acne sunken scar were treated in the Department of Burn and Plastic Surgery of the Second People's Hospital of Jiaozuo City,Henan Province.They were randomly divided into two groups with 48 cases in each group.The control group was treated with routine therapy and the observation group was treated with pixel 2940 nm erbium laser combined with vitamin B12.The therapeutic effects,acne scar weight score(ECCA),skin condition and adverse reactions were compared between the two groups.Results The total effective rate of the control group was 77.08%(37/48),which was lower than that of the observation group 91.67%(44/48)(P<0.05);The incidence of adverse reactions,pore and amethyst in ECCA score of the control group were(18.14±9.33),18.75%(9/48),(32.25±8.41)and(18.24±5.12),which were higher than those of the observation group(26.45±12.60),4.17%(2/48),(28.24±7.52)and(15.63±4.34)(P<0.05),respectively.Conclusions Pixel 2940 nm erbium laser combined with vitamin B12 is effective in the treatment of acne sunken scar,with less adverse reactions and high safety.It is worthy of clinical application.

关 键 词：寻常痤疮 维生素B12 凹陷性瘢痕 铒激光 2940nm 

分 类 号：R758.733[医药卫生—皮肤病学与性病学]