黑索今神经毒性研究进展  

Research progress on neurotoxicity of hexogen

作　　者：高婷 刘志永 高永超 李存治 赵彬 李欢 樊朋 高俊宏 GAO Ting;LIU Zhi-yong;GAO Yong-chao;LI Cun-zhi;ZHAO Bin;LI Huan;FAN Peng;GAO Jun-hong(CNGC Institute of Industrial Health,Xi'an 710065,China)

机构地区：[1]兵器工业卫生研究所,陕西西安710065

出　　处：《中国工业医学杂志》2022年第1期42-44,共3页Chinese Journal of Industrial Medicine

摘　　要：黑索今(hexogen,RDX)为一种具有高度爆炸性的化合物,由于性能良好被广泛应用于军事和工业中,其带来的健康损害同时也越来越受到关注。本文现对近年来RDX的一般毒性、毒代动力学及神经毒性机制等研究资料进行汇总,为RDX神经毒性机制的深入研究奠定基础。Hexogen(RDX)is a highly explosive compound,which is widely used in military and industries due to its good performance.With the wide use of RDX,the health damage by it has also attracted more and more attention.In this paper,the general toxicity,toxicokinetics,neurotoxicity and its mechanism of RDX were summarized,thereby to lay a foundation for the fur⁃ther study of the neurotoxicity mechanism of RDX.

关 键 词：黑索今(RDX) 毒代动力学 神经毒性 机制 

分 类 号：R994.3[医药卫生—毒理学]