三维斑点追踪成像技术对单纯性肥胖儿童左心室收缩功能的评价及其与外周动脉弹性相关性的前瞻性研究  

Value of three-dimensional speckle-tracking imaging in evaluating left ventricular systolic function and its correlation with peripheral arterial elasticity in children with simple obesity:a prospective study

作　　者：周丽 王淑霞 王芳 曹伟 王婷婷 叶晶晶 納丽莎 赵海萍 ZHOU Li;WANG Shu-Xia;WANG Fang;CAO Wei;WANG Ting-Ting;YE Jing-Jing;NA Li-Sha;ZHAO Hai-Ping(Department of Cardiac Functions Examination,General Hospital of Ningxia Medical University,Yinchuan 750004,China)

机构地区：[1]宁夏医科大学总医院心脏中心功能部,宁夏银川750004 [2]宁夏医科大学公共卫生与管理学院,宁夏银川750004

出　　处：《中国当代儿科杂志》2022年第5期566-571,共6页Chinese Journal of Contemporary Pediatrics

基　　金：国家自然科学基金(81860582);宁夏自然科学基金(2022AAC03603)。

摘　　要：目的应用三维斑点追踪成像技术评价单纯性肥胖儿童左心室收缩功能,并探讨其与外周动脉弹性的相关性。方法采用随机结合方便抽样的方法,获取研究样本。将样本分为3组:肥胖组(23例)、超重组(21例)和正常组(24例)。采用三维斑点追踪成像技术测量左心室整体长轴应变(global longitudinal strain,GLS)、整体径向应变(global radial strain,GRS)及整体环向应变(global circumferential strain,GCS),全自动动脉硬化测试仪测量踝臂指数(ankle brachial index,ABI)、脉搏波传导速度(brachial ankle pulse wave velocity,baPWV)。比较3组各参数的差异性并探讨三维斑点追踪各参数与ABI、baPWV的相关性。结果肥胖组与正常组左心室GLS、GRS、GCS差异无统计学意义(P>0.05)。超重组左心室GLS高于正常组[(-24±7)vs(-19±12),P<0.05]。肥胖组ABI(1.00±0.09)、超重组ABI(1.09±0.13)均低于正常组(2.25±0.13)(P<0.05);肥胖组baPWV高于正常组[(978±109)vs(905±22),P<0.05]。肥胖儿童左心室GLS与baPWV呈正相关(r=0.516,P<0.05),与ABI无相关性(P>0.05);左心室GCS、GRS与ABI、baPWV无相关性(P>0.05)。结论单纯性肥胖儿童左心室收缩功能和外周动脉弹性发生不同程度的改变且二者有一定的相关性。Objective To study the application of three-dimensional speckle-tracking imaging in evaluating left ventricular systolic function and its correlation with peripheral arterial elasticity in children with simple obesity.Methods Random sampling combined with convenience sampling was used to obtain research samples,and then the samples were divided into an obesity group(23 cases),an overweight group(21 cases),and a normal group(24 cases).Three-dimensional speckle-tracking imaging was used to measure the global longitudinal strain(GLS),global radial strain(GRS),and global circumferential strain(GCS)of the left ventricle.An automatic arteriosclerosis tester was used to measure ankle-brachial index(ABI)and brachial-ankle pulse wave velocity(baPWV).These parameters were compared among the three groups.The correlation of three-dimensional speckle-tracking parameters with ABI and baPWV was evaluated.Results There were no significant differences in GLS,GRS,and GCS between the obesity and normal groups(P>0.05).The overweight group had a significantly higher GLS than the normal group[(-24±7)vs(-19±12),P<0.05].The obesity and overweight groups had a significantly lower ABI than the normal group[(1.00±0.09)/(1.09±0.13)vs(2.25±0.13),P<0.05).The obesity group had a significantly higher baPWV than the normal group[(978±109)vs(905±22),P<0.05].In the children with obesity,GLS was positively correlated with baPWV(r=0.516,P<0.05),but not correlated with ABI(P>0.05),and GCS and GRS had no significant correlation with ABI or baPWV(P>0.05).Conclusions There are varying degrees of changes in left ventricular systolic function and peripheral arterial elasticity in children with simple obesity,and there is a certain correlation between them.

关 键 词：肥胖 三维斑点追踪成像技术 弹性 相关性 儿童 

分 类 号：R723.14[医药卫生—儿科]