藤本类中药“通络”传统认识与共性机制研究现状  

Research status of traditional knowledge and common mechanisms on dredging collaterals of rattan medicine

作　　者：赵光瑞 石芸[2] 高珣 金俊杰 蔡宝昌[2,3] 李伟东 秦昆明[1,4] ZHAO Guang-rui;SHI Yun;GAO Xun;JIN Jun-jie;CAI Bao-chang;LI Wei-dong;QIN Kun-ming(School of Pharmacy,Jiangsu Ocean University,Lianyungang 222005,China;School of Pharmacy,Nanjing University of Chinese Medicine,Nanjing 210046,China;Nanjing Haiyuan Chinese Medicine Pieces Co.,Ltd.,Nanjing 210061,China;Lianyungang Guike Pharmaceutical Co.,Ltd.,Lianyungang 222000,China)

机构地区：[1]江苏海洋大学药学院,江苏连云港222005 [2]南京中医药大学药学院,江苏南京210046 [3]南京海源中药饮片有限公司,江苏南京210061 [4]连云港贵科药业有限公司,江苏连云港222000

出　　处：《中草药》2022年第8期2517-2525,共9页Chinese Traditional and Herbal Drugs

基　　金：江苏省六大人才高峰项目(SWYY-108);江苏省高校优秀科技创新团队项目。

摘　　要：藤本类中药是传统中药的重要组成部分,临床常用于多种病症的治疗。中医理论认为“藤本入络”,藤本类药物的临床应用领域也体现了该理论。现代研究发现中医络病与西医的各类血管病变具有相关性,以血管反应为中心的渗出性病变是炎症的重要标志。因此,从抗炎作用的角度探讨藤本类中药“通络”作用的共性机制,对于藤本类中药的药效作用机制研究具有指导意义。将临床常用的藤本类中药按辛温通络、活血通络、清热解毒通络分类,分别从传统功效分类与现代研究2个方面进行比较分析,从抗炎作用角度探讨藤本类中药的“通络”作用的共性机制,为藤本类中药的临床开发应用提供指导。Rattan medicine is an important part of traditional Chinese medicine, which is often used in treatment of many diseases in clinic.According to the theory of traditional Chinese medicine “rattan medicine can dredge collaterals”, and the clinical application of rattan medicine also reflects the words.Modern researches show that collateral diseases are related to various vascular diseases in Western medicine, and the exudative disease centered on vascular reaction is an important sign of inflammation.Therefore, it is significant to study the mechanism of dredging collaterals from the anti-inflammatory point of view for study of the pharmacodynamic mechanism of rattan medicine.Rattan medicine commonly used in clinic are divided into warm-pungent and dredging collaterals, activating blood circulation and dredging collaterals, and heat-clearing, toxin-resolving and dredging collaterals, and they are compared from traditional knowledge and common mechanisms in this paper.Common mechanism of dredging collaterals from the view of anti-inflammation are explored, in order to provide guidance for clinical development and application of rattan medicine.

关 键 词：藤本类中药 药性 络病学 炎症 辛温通络 活血通络 清热解毒通络 

分 类 号：R282.710.5[医药卫生—中药学]