2021年桂林市秀峰区1~69岁居民乙肝和丙肝血清流行病学调查  

Sero-epidemiological study of hepatitis B and hepatitis C among residents aged 1~69 years in Xiufeng District of Guilinin City in 2021

作　　者：高倩 周云[3] 秦春林[3] 黄恺 王琪 张宠 殷磊 魏兵 Gao Qian;Zhou Yun;Qin Chunlin;Huang Kai;Wang Qi;Zhang Chong;Yin Lei;Wei Bing(School of Public Health,Guilin Medical University,Guilin 541199,Guangxi,China;Science Experiment Center,Guilin Medical University,Guilin 541199,Guangxi,China;Guilin Center for Disease Control and Prevention,Guilin 541001,Guangxi,China;College of International Education,Guilin Medical University,Guilin 541199,Guangxi,China)

机构地区：[1]桂林医学院公共卫生学院,广西桂林541199 [2]桂林医学院科学实验中心,广西桂林541199 [3]广西桂林市疾病预防控制中心,广西桂林541001 [4]桂林医学院国际教育学院,广西桂林541199

出　　处：《右江民族医学院学报》2022年第2期276-279,共4页Journal of Youjiang Medical University for Nationalities

基　　金：桂林医学院公共卫生学院2020年联合培养基地研究生教育创新计划项目(GWXY202005)。

摘　　要：目的了解现阶段桂林市秀峰区人群乙型病毒性肝炎(HBV)和丙型病毒性肝炎(HCV)流行和血清免疫状况,评估肝炎防治工作及成效,为制定新的防控策略提供理论基础。方法通过二阶段整群随机抽样的方法抽取秀峰区1~69岁人群707名进行乙肝和丙肝的血清流行病学调查。采集调查对象静脉血3~5ml,使用ELISA法对样本进行HBsAg、HBsAb、HBcAb及HCV-Ab检测。结果调查对象HBsAg总阳性率为7.50%,抗-HBs总阳性率为62.38%,抗-HBc总阳性率为53.47%,各年龄组之间HBsAg、抗-HBs和抗-HBc阳性率的差异具有统计学意义(P<0.05)。共检测出HCV阳性4例,男女各2例,年龄分布为40~49岁1例,50~59岁3例。结论秀峰区人群HBsAg及抗-HBc阳性率较往年有所提升,抗-HCV阳性率低于我国人群一般水平。应加强乙肝疫苗接种,完善对肝炎病毒传染源和传播途径的监管。Objective To investigate the prevalence of viral hepatitis B(HBV)and viral hepatitis C(HCV)and the status of serum immunity of population in Xiufeng District,Guilin,so as to evaluate the work and achievement of prevention and control of hepatitis and to provide theoretical basis for formulating new prevention and control strategies.Methods The method of two-stage cluster random sampling was adopted to select 707people aged 1~69years from Xiufeng District to conduct a sero-epidemiological investigation of hepatitis B and hepatitis C among them.3~5ml of venous blood was collected from the respondents,and their HBsAg,HBsAb,HBcAb and HCV-Ab were detected by ELISA.Results The total positive rate of HBsAg was 7.50%.The total positive rate of anti-HBs was 62.38%and the total positive rate of anti-HBc was 53.47%.There were significant differences in the positive rate of HBsAg,anti-HBs and anti-HBc among different age groups(P<0.05).A total of 4cases(2males and 2females)were tested positive for HCV,with 1case aged40~49years and 3cases aged 50~59years.Conclusion The positive rates of HBsAg and anti-HBc in Xiufeng District are higher than those in previous years,while the positive rate of anti-HCV is lower than the general level of Chinese population.Hepatitis B vaccine inoculation should be strengthened,and the supervision of infection sources and transmission channels should be improved.

关 键 词：乙肝 丙肝 血清流行病学 免疫规划 

分 类 号：R512.6[医药卫生—内科学] R181.3[医药卫生—临床医学]