合并卵圆孔未闭的阵发性心房颤动射频消融治疗  

Impact of a patent foramen ovale on paroxysmal atrial fibrillation ablation

作　　者：王涛[1] 岳庆雄[2] 庞占琪[1] 王琳[1] 杨健[1] 董赫[1] 李亚文[1] 马亮 李世军[1] WANG Tao;YUE Qing-xiong;PANG Zhan-qi;WANG Lin;YANG Jian;DONG He;MA Liang;LI Ya-wen;LI Shi-jun(Department of Cardiolo­gy,Dalian Municipal Central Hospital affiliated of Dalian Medical University,Dalian 116033,Liaoning,China;Department of Ultrasound,Dalian Municipal Central Hospital affiliated of Dalian Medical University,Dalian 116033,Liaoning,China)

机构地区：[1]大连市中心医院心内五科,辽宁大连116033 [2]大连市中心医院超声科,辽宁大连116033

出　　处：《中国心脏起搏与心电生理杂志》2022年第2期134-137,共4页Chinese Journal of Cardiac Pacing and Electrophysiology

基　　金：吴阶平医学基金会资助项目(编号320.6750.19089-10)。

摘　　要：目的 研究合并卵圆孔未闭(PFO)的阵发性心房颤动(简称房颤)患者的临床特点。方法 顺序入选2018年1月至2019年12月接受射频消融治疗的阵发性房颤患者,术式为肺静脉电隔离为终点的环肺静脉消融术,行经食管超声观察患者有无PFO,根据有无PFO分为PFO组及非PFO组,比较两组患者的临床特点及消融效果。结果 阵发性房颤181例(男性101例,女性80例),其中PFO组28例,非PFO组153例,PFO组更加年轻[(58.6±9.3)岁vs (62.9±9.2)岁,P=0.025],PFO组左房有增大趋势[(39.7±4.9)mm vs (38.4±4.8) mm,P=0.098];两组射频消融成功率无差别(82.1%vs 81.7%,P=0.598)。结论 经食管超声发现合并PFO的阵发性房颤患者射频消融成功率与未合并PFO患者无差别,但PFO可能参与房颤的提前发生。Objective To investigate the impact of a patent foramen ovale(PFO) on paroxysmal atrial fibrillation(PAF) ablation. Method From January 2018 to December 2019, PAF patients underwent circumferential pulmonary veins(PV) catheter ablation with the endpoint being PV electrical isolation of all was enrolled. The presence of a PFO was determined by transesophageal echocardiography. According to with or without the presence of PFO, the PAF patients were divided into PFO groups and non-PFO group. Clinical follow-up was also investigated. The clinical parameters between the two groups of patients were compared. Results 181 AF patients(101 males, 80 females) were enrolled. A PFO was detected in 28 patients by transesophageal echocardiography which were enrolled in PFO group. Patients in PFO group were younger [(58.6±9.3) years vs(62.9±9.2) years, P=0.025]. There was no difference between PFO group and non-PFO group in left atrial diameter [(39.7±4.9)mm vs(38.4±4.8) mm, P=0.098]. After a mean follow-up of(19±7) months, there was no difference in the outcome of catheter ablation between the two groups(82.1% vs 81.7%,P=0.598). Conclusion Success is not affected when AF combining a PFO compared with AF without combining a PFO;PFO related left atria enlarge may lead to AF appear ahead.

关 键 词：心血管病学 心房颤动 卵圆孔未闭 年龄 左房大小 

分 类 号：R541.75[医药卫生—心血管疾病] R454.1[医药卫生—内科学]