腹泻对ICU成人患者临床结局影响的Meta分析  

Clinical outcomes of adult patients with diarrhea in ICU:A systematic review and Meta-analysis

作　　者：孔佳佳 李娜[1] 程洁 王瑞[1] 张志刚[1,2] 韩露露[1] 张彩云 Kong Jia-jia;Li Na;Cheng Jie;Wang Rui;Zhang Zhi-gang;Han Lu-lu;Zhang Cai-yun(College of Nursing,Lanzhou University,Lanzhou 730000,China;Intensive Care Unit,The First Hospital of Lanzhou University,Lanzhou 730000,China;Outpatient Department,The First Hospital of Lanzhou University,Lanzhou 730000,China)

机构地区：[1]兰州大学护理学院,甘肃兰州730000 [2]兰州大学第一医院重症监护室,甘肃兰州730000 [3]兰州大学第一医院门诊部,甘肃兰州730000

出　　处：《兰州大学学报（医学版）》2022年第4期39-44,共6页Journal of Lanzhou University（Medical Sciences）

摘　　要：目的系统评价ICU成人患者腹泻对其结局的影响。方法计算机系统检索PubMed、中国知识基础设施工程等8个数据库建库至2021年9月1日腹泻对ICU成人患者临床结局影响的相关文献。由2名研究者根据纳入排除标准独立筛选文献、资料提取及评价文献质量,用RevMan5.3软件分析数据。结果共纳入8篇队列研究,患者19294例。Meta分析结果显示,腹泻会增加ICU死亡率、90天死亡率,延长ICU住院时间、总住院时间及机械通气时间,增加压疮发生率。结论ICU成人患者腹泻与死亡率增加,ICU住院时间、总住院时间及机械通气天数延长,压疮发生率增加有关。Objective To systematically evaluate the effect of diarrhea on the outcomes in adult ICU patients.Methods Literature related to clinical outcomes of diarrhea in adult intensive care unit(ICU)patients from 8databases,including PubMed and China National Knowledge Infrastructure,up to September 1,2021,were searched via the computer system.Literature screening,data extraction and quality evaluation were conducted by 2 researchers according to the inclusion criteria,and Revman 5.3 software was used for Meta-analysis.Results A total of 8 cohort studies involving 19294 patients were included.Meta-analysis results showed that diarrhea increased ICU mortality,90-day mortality,extended length of stay in the ICU,length of stay in the hospital and mechanical ventilation duration,and also increased the incidence of pressure ulcers.Conclusion Available evidence suggests that diarrhea in adult ICU patients is associated with increased mortality,length of ICU stay,length of hospital stay and length of mechanical ventilation,and increased incidence of pressure ulcers.

关 键 词：危重症 腹泻 结局 META分析 

分 类 号：R446.1[医药卫生—诊断学]