Allium覆膜金属输尿管支架治疗输尿管狭窄的疗效分析  

Clinical Analysis of Allium Coated Metal Ureteral Stent in the Treatment of Ureteral Stricture

作　　者：石兵 赵凡 朱建[1] 解吕中[1] 王伟[1] Shi Bing;Zhao Fan;Zhu Jian(Department of Urological Surgery,Nantong Hospital of Traditional Chinese Medicine,Nantong Hospital Affiliated to Nanjing University of Chinese Medicine,Nantong 226001,China;不详)

机构地区：[1]南通市中医院南京中医药大学南通附属医院泌尿外科,南通226001 [2]南通大学附属医院泌尿外科,南通226001

出　　处：《中国微创外科杂志》2022年第5期407-411,共5页Chinese Journal of Minimally Invasive Surgery

基　　金：南通市卫计委课题青年项目(WKZL2018036)。

摘　　要：目的探讨Allium覆膜金属输尿管支架治疗输尿管狭窄的有效性和安全性。方法回顾性分析2020年6月~2021年6月输尿管狭窄19例资料,共置入Allium覆膜金属输尿管支架20根,随访3个月,记录不良反应事件。对19例术前和术后3个月肾盂宽度及尿常规白细胞、红细胞计数,17例留置双J管者术前和术后3个月输尿管支架相关症状问卷(Ureteral Stent Symptom Questionnaire,USSQ)进行比较。结果19例(20侧)手术顺利,均置入成功。随访3个月,1例(5%,1/20)术后3个月支架上移。术后3个月泌尿系B超肾盂宽度[(1.5±0.2)cm]较术前[(2.1±0.5)cm]明显缩小(t=6.562,P=0.000),尿白细胞计数和红细胞计数均较术前明显减少(P<0.01)。17例术前留置双J管者USSQ问卷总分[(34.2±3.6)分]较术前[(61.2±6.9)分]明显降低(t=19.356,P=0.000),包括下尿路症状、躯体疼痛症状、一般健康状态、工作能力评分均明显降低(P<0.01)。结论Allium覆膜金属输尿管支架置入治疗输尿管狭窄安全有效,可以明显改善肾盂积水和生活质量,其远期疗效仍需要大样本量长时间随访。Objective To evaluate the efficacy and safety of Allium coated metal ureteral stent in the treatment of ureteral stricture.Methods Clinical data of 19 cases of ureter stricture treated with Allium coated metal ureteral stent from June 2020 to June 2021 were retrospectively analyzed.A total of 20 ureter stents(Allium coated metal ureteral stent)were implanted.All the patients were followed up for 3 months,and adverse events were recorded.The width of renal pelvis and urinary leukocyte and erythrocyte count were compared before and 3 months after operation in the 19 patients.The scores of Ureteral Stent Symptom Questionnaire(USSQ)before and 3 months after operation were analyzed in 17 patients with indwelling double-J stent.Results The operation was successful in all the 19 patients.After 3 months,an Allium stent shifted up in a patient,and the displacement rate was 5%(1/20).The width of renal pelvis was significantly smaller than that before operation[(1.5±0.2)cm vs.(2.1±0.5)cm,t=6.562,P=0.000].The urinary leukocyte and erythrocyte count were also significantly reduced(P<0.01).The total score of USSQ in 17 patients with retention of double-J tube was significantly lower than that before operation[(34.2±3.6)vs.(61.2±6.9)points,t=19.356,P=0.000],including urinary symptoms(US)score,body pain(BP)score,physical condition(PC)score,and work performance(WP)score(P<0.01).Conclusions Allium coated metal ureteral stent implantation is safe and effective in the treatment of ureteral stricture,which can significantly improve the renal function and quality of life of patients.The long-term efficacy of Allium covered metal ureteral stent still needs to be further studied with large sample size.

关 键 词：输尿管狭窄 覆膜金属输尿管支架 Allium支架 有效性 安全性 

分 类 号：R69[医药卫生—泌尿科学]