舒芬太尼靶控输注的临床应用进展  

Clinical application progress of sufentanil target-controlled infusion

作　　者：丁慧萍 宦烨 王雯(综述)[1] 蔡宏伟(审校)[1] DING Huiping;HUAN Ye;WANG Wen;CAI Hongwei(Department of Anesthesiology,Xiangya Hospital,Central South University,Changsha 410000,China)

机构地区：[1]中南大学湘雅医院麻醉科,长沙410000

出　　处：《临床与病理杂志》2022年第4期990-994,共5页Journal of Clinical and Pathological Research

基　　金：湖南省科技厅重点研发计划项目(2017SK2034);中南大学湘雅医院麻醉科科研项目(3302012014002)。

摘　　要：靶控输注(target-controlled Infusion,TCI)是在输注静脉麻醉药物时应用药代动力学和药效动力学原理,通过调节目标(血浆或效应室)的药物浓度来控制或维持麻醉深度。舒芬太尼TCI广泛应用于不同手术的麻醉,本文将主要介绍舒芬太尼TCI在全麻的诱导和气管插管、心脏手术、需要术中唤醒手术、病态肥胖患者手术以及术后镇痛中的应用,旨在为今后的临床应用和基础研究提供理论参考。Target-controlled Infusion(TCI)is the application of pharmacokinetics and pharmacodynamic principles when intravenous anesthetics are infused,and the depth of anesthesia is controlled or maintained by adjusting the drug concentration of the target(plasma or effect chamber).Sufentanil TCI is widely used in anesthesia for different operations.This article summarizes domestic and foreign literature,to give an introduction of sufentanil TCI in induction of general anesthesia and tracheal intubation,cardiac surgery,surgery that requires intraoperative wakeup,surgery for morbidly obese patients and the application of postoperative analgesia,with an aim to provide theoretical references for future clinical applications and basic research.

关 键 词：舒芬太尼 靶控输注 麻醉 

分 类 号：R614[医药卫生—麻醉学]