自身免疫性疱病与银屑病的相关性  

Correlation between autoimmune bullous diseases and psoriasis

作　　者：闪莹 左亚刚 Shan Ying;Zuo Yagang(Department of Dermatology,National Clinical Research Center for Skin and Immune Diseases,Translational Medicine Center of Peking Union Medical College Hospital,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100730,China;Department of Dermatology,Graduate School of Hebei North University,Zhangjiakou 075000,Hebei,China)

机构地区：[1]中国医学科学院、北京协和医学院北京协和医院皮肤科协和医学转化中心国家皮肤与免疫疾病临床医学研究中心,北京100730 [2]河北北方学院,张家口075000

出　　处：《中华皮肤科杂志》2022年第5期452-455,共4页Chinese Journal of Dermatology

基　　金：国家自然科学基金(81972944);北京市自然科学基金(7192166)。

摘　　要：自身免疫性疱病(AIBD)和银屑病的发病机制有部分相似性。近年来,多项研究报道银屑病与AIBD之间具有相关性,以大疱性类天疱疮多见,还包括寻常型天疱疮、红斑型天疱疮、线状IgA大疱性皮病等,多数AIBD在银屑病发病后发生,部分患者两病同时出现或AIBD先出现。本文综述AIBD与银屑病发病的相关性及可能存在的机制。There are overlaps in pathogenesis between autoimmune bullous diseases(AIBDs)and psoriasis.In recent years,there have been many reports on correlations between psoriasis and AIBDs.Bullous pemphigoid is the most common AIBD associated with psoriasis,followed by pemphigus vulgaris,pemphigus erythematosus and linear IgA bullous dermatosis.AIBDs occur after the onset of psoriasis in most cases,but simultaneously with or before the onset of psoriasis in some patients.This review summarizes correlations between AIBDs and psoriasis,as well as possible mechanisms.

关 键 词：银屑病 皮肤疾病 水疱大疱性 自身免疫疾病 天疱疮 类天疱疮 大疱性 

分 类 号：R758.6[医药卫生—皮肤病学与性病学]