超早期小骨窗颅内血肿清除术治疗高血压基底节区出血的临床效果  

Clinical effect of ultra-early small bone window intracranial hematoma removal in the treatment of hemorrhage in basal ganglia of hypertension

作　　者：陈西亚 CHEN Xiya(Department of Neurosurgery,Wuhan Xinzhou District People′s Hospital,Hubei Province,Wuhan430400,China)

机构地区：[1]武汉市新洲区人民医院神经外科,湖北武汉430400

出　　处：《中国当代医药》2022年第10期85-88,共4页China Modern Medicine

摘　　要：目的 探讨超早期小骨窗颅内血肿清除术治疗高血压基底节区出血的临床效果。方法 选取2019年1月至2021年1月武汉市新洲区人民医院收治的81例高血压基底节区出血患者作为研究对象,按照随机数字表法分为观察组(41例)与对照组(40例)。观察组采用超早期小骨窗颅内血肿清除术,对照组采用传统骨瓣开颅血肿清除术。比较两组患者的血肿清除率、手术时间、术中出血量、治疗效果及手术前后的神经元特异性烯醇化酶(NSE)、S100蛋白(S100)动态变化情况,记录两组的并发症发生情况。结果 观察组的术中出血量少于对照组,手术时间短于对照组,差异有统计学意义(P<0.05)。观察组术后各时间点的S100及NSE水平低于对照组,差异有统计学意义(P<0.05)。两组的不良反应发生率比较,差异无统计学意义(P>0.05)。结论 超早期小骨窗颅内血肿清除术与大骨瓣开颅血肿清除术对高血压脑出血的治疗效果相当,安全性相当,但前者在手术时间、出血量、对患者创伤方面更具优势。Objective To investigate the clinical effect of ultra-early small bone window intracranial hematoma removal in the treatment of hemorrhage in the basal ganglia of hypertension.Methods A total of 81 patients with hemorrhage in the basal ganglia of hypertension admitted to Wuhan Xinzhou District People′s Hospital from January 2019 to January 2021 were selected as the research objects,they was divided into the observation group(41 cases)and the control group(40 cases)according to random number table method.The observation group used the ultra-early small bone window intracranial hematoma removal,and the control group performed traditional bone valve craniotomy hematoma clearance.The hematoma clearance rate,operation time,intraoperative bleeding volume,the treatment effect and the dynamic changes of neuron-specific enolase(NSE)and S100 protein(S100)before and after operation were compared between the two groups,and the complications of the two groups were recorded.Results The amount of bleeding of the observation group was lower than that of the control group,and the operation time of the observation group was shorter than that of the control group,there were statistically significant(P<0.05).The levels of S100 and NSE at the time points of the observation group were lower than those of the control group,and there were statistically significant(P<0.05).There was no statistically significant in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Ultra-early small bone window intracranial hematoma removal and large bone flap craniotomy removal are equivalent in the treatment of hypertensive cerebral hemorrhage,and the security is equivalent,but the former has more advantages in terms of operation time,blood loss,and trauma to the patient.

关 键 词：超早期小骨窗颅内血肿清除术 高血压 基底节区出血 神经元特异性烯醇化酶 

分 类 号：R651.15[医药卫生—外科学]